Evaluating serum ferritin levels in patients with diabetic ketoacidosis
Official title: Role of Ferritin in the Clinical Presentation and Short-Term Prognosis of Diabetic Ketoacidosis
Run by Sohag University · NCT06748365 · Data updated 2026-11-12
This study is testing if measuring ferritin levels in adults with diabetic ketoacidosis can help predict how severe their condition is and what their short-term outcomes might be.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag, Sohag Governorate) |
| Status | Recruiting |
| Started | January 1, 2025 |
| Main results expected | January 2026 |
| Study ends | February 2026 |
| Registry record updated | May 14, 2025 |
| Trial ID | NCT06748365 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 years and older with a diagnosis of diabetic ketoacidosis.
✕Probably not a fit
Patients with chronic inflammatory diseases, infections, or other acute complications such as myocardial infarction or stroke may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the relationship between serum ferritin levels and the clinical presentation and short-term prognosis of patients experiencing diabetic ketoacidosis (DKA). By analyzing the correlation between ferritin levels and the severity of DKA at presentation, the study seeks to determine the prognostic value of ferritin in predicting short-term outcomes. The study will include adult patients diagnosed with DKA according to established criteria while excluding those with chronic conditions that may confound results.
Why it matters
Potential benefit: If successful, this study could provide a new prognostic tool for clinicians to better predict outcomes in DKA patients based on serum ferritin levels.
How similar studies have gone: While previous studies have explored the correlation of ferritin with other acute conditions, this approach in DKA patients is novel and has not been tested before.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: \- All patients with DKA : 1. Adult Aged 18 years old or older . 2. Type 1 DM , type 2 DM 3. Diagnosis of DKA based on the American Diabetes Association criteria: blood glucose \>250 mg/dL, arterial pH \<7.3, serum bicarbonate \<18 mEq/L, Exclusion Criteria: 1. Patients age less than 18 years old 2. Iron deficiency anemia and iron overload 3. Chronic Inflammatory Diseases: Conditions such as rheumatoid arthritis, systemic lupus erythematosus, and inflammatory bowel disease 4. Acute and chronic infections, including bacterial, viral, and fungal infections 5. Pt presented with other acute complication (MI,stroke) 6. CKD patients 7. Patients with chronic liver diseases 8. Patients with malignancy 9. Pregnant women.
Where it's running
-
Sohag university Hospitals
Sohag, Sohag Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Joseph Medhat Sobhy, resident in internal medicine
- Email: joeisgreatyeah@gmail.com
- Phone: +2001011041077
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Perfusion index in the emergency department to gauge DKA severity
This study tests whether the perfusion index measured at ED admission can help predict how severe diabetic ketoacidosis will be in adults.
-
Markers of early kidney and heart injury in children newly diagnosed with type 1 diabetes
This study will test whether blood markers and heart ultrasound can find early kidney or heart injury in children aged 2–16 who are newly diagnosed with type 1 diabetes, comparing those with diabetic ketoacidosis, those without, and healthy children.
-
Recognizing dapagliflozin overdose in ICU patients admitted for metformin poisoning.
This project will see if clinical signs and routine lab tests can help doctors tell whether adults in the ICU for metformin poisoning also took too much dapagliflozin.
-
Intravenous arginine to help treat diabetic ketoacidosis in people with type 2 diabetes
This study tests whether a single IV dose of arginine given early in DKA can safely boost your own insulin and help adults with ketone-prone type 2 diabetes recover faster.
-
Using REAMBERIN® for treating diabetic ketoacidosis
This study is testing if adding a new treatment called REAMBERIN® to standard care can help people with diabetic ketoacidosis recover faster and leave the hospital sooner.
-
Testing a new device for continuous glucose and ketone monitoring in healthy individuals
This study is testing a new device that continuously checks glucose and ketone levels in healthy people to see if it can help manage diabetes better and prevent serious complications.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.