Evaluating serum ferritin levels in patients with diabetic ketoacidosis
Role of Ferritin in the Clinical Presentation and Short-Term Prognosis of Diabetic Ketoacidosis
This study is testing if measuring ferritin levels in adults with diabetic ketoacidosis can help predict how severe their condition is and what their short-term outcomes might be.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag, Sohag Governorate) |
| Trial ID | NCT06748365 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the relationship between serum ferritin levels and the clinical presentation and short-term prognosis of patients experiencing diabetic ketoacidosis (DKA). By analyzing the correlation between ferritin levels and the severity of DKA at presentation, the study seeks to determine the prognostic value of ferritin in predicting short-term outcomes. The study will include adult patients diagnosed with DKA according to established criteria while excluding those with chronic conditions that may confound results.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 years and older with a diagnosis of diabetic ketoacidosis.
Not a fit: Patients with chronic inflammatory diseases, infections, or other acute complications such as myocardial infarction or stroke may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a new prognostic tool for clinicians to better predict outcomes in DKA patients based on serum ferritin levels.
How similar studies have performed: While previous studies have explored the correlation of ferritin with other acute conditions, this approach in DKA patients is novel and has not been tested before.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: \- All patients with DKA : 1. Adult Aged 18 years old or older . 2. Type 1 DM , type 2 DM 3. Diagnosis of DKA based on the American Diabetes Association criteria: blood glucose \>250 mg/dL, arterial pH \<7.3, serum bicarbonate \<18 mEq/L, Exclusion Criteria: 1. Patients age less than 18 years old 2. Iron deficiency anemia and iron overload 3. Chronic Inflammatory Diseases: Conditions such as rheumatoid arthritis, systemic lupus erythematosus, and inflammatory bowel disease 4. Acute and chronic infections, including bacterial, viral, and fungal infections 5. Pt presented with other acute complication (MI,stroke) 6. CKD patients 7. Patients with chronic liver diseases 8. Patients with malignancy 9. Pregnant women.
Where this trial is running
Sohag, Sohag Governorate
- Sohag university Hospitals — Sohag, Sohag Governorate, Egypt (Recruiting)
Study contacts
- Study coordinator: Joseph Medhat Sobhy, resident in internal medicine
- Email: joeisgreatyeah@gmail.com
- Phone: +2001011041077
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.