Evaluating self-sampling versus clinician-sampling for HPV testing in cervical cancer screening

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the effectiveness of self-sampling for HPV DNA testing compared to traditional clinician-sampling in primary care settings. It is a multi-center, randomized controlled trial where participants will be offered either clinician-sampling or, if declined, self-sampling for HPV testing. The primary goal is to determine if self-sampling increases the detection rates of high-risk HPV DNA by at least 7.7%. The findings will provide insights into the feasibility and cost-effectiveness of implementing self-sampling in routine cervical cancer screening.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 30-69 years old female Singapore citizens
* Due for cervical cancer screening
* Engaged in sexual intercourse before
* Able to give informed consent
* Able to read and communicate in English, Chinese or Malay

Exclusion Criteria:

* Virgo intacta
* Pregnancy
* History of cervical cancer, precancerous cervical lesions and total hysterectomy

Where it's running

• National Healthcare Group Polyclinics
  Singapore, Singapore, Singapore Recruiting

Study contacts

• Principal investigator: Ng Xin Rong, MBBS — National Healthcare Group Polyclinics
• Study coordinator: Ng Xin Rong, MBBS
• Email: xin_rong_ng@nhgp.com.sg
• Phone: +65 63553000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.