Evaluating salivary cortisol levels in patients with temporomandibular disorder
Assessment of Salivary Cortisol As a Biomarker in Patients with Temporomandibular Disorder
This study is testing if people with Temporomandibular Disorders have higher levels of the stress hormone cortisol in their saliva compared to those without the condition.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Coimbra Academic / other |
| Locations | 1 site (Coimbra, Coimbra District) |
| Trial ID | NCT06874868 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess whether patients with Temporomandibular Disorders (TMD) exhibit elevated levels of salivary cortisol compared to individuals without the disorder. Participants will be evaluated using the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) to classify them into study and control groups. Saliva samples will be collected from participants to measure cortisol levels, providing insights into the potential link between TMD and psychological factors such as anxiety. The study will take place at the Faculty of Medicine of the University of Coimbra.
Who should consider this trial
Good fit: Ideal candidates for this study are patients attending the dental clinic at the Faculty of Medicine of the University of Coimbra who have been diagnosed with TMD.
Not a fit: Patients who are pregnant, minors, or non-autonomous individuals will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of the relationship between cortisol levels and TMD, potentially leading to improved diagnostic and treatment strategies.
How similar studies have performed: While there is existing research on cortisol as a biomarker in psychological disorders, this specific approach in relation to TMD is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who attend the dental clinic of the Faculty of Medicine of University of Coimbra Exclusion Criteria: * Pregnant women, minors and non-autonomous individuals
Where this trial is running
Coimbra, Coimbra District
- Faculty of Medicine of University of Coimbra — Coimbra, Coimbra District, Portugal (Recruiting)
Study contacts
- Study coordinator: Bruno Macedo, PhD
- Email: brunomacsousa@gmail.com
- Phone: +351-239 249 151
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.