Evaluating risk assessment tools for managing blood clots in heart surgery patients

Predictive Efficacy of Modified Caprini Score and D-Dimer for the Evaluation and Management of Lower Extremity Venous Thrombosis Among Cardiothoracic Surgery Patients in Baghdad

Observational Al-Nahrain University · NCT06729021

This study is testing if using a specific risk score along with blood tests can better predict and manage blood clots in patients having heart surgery.

Quick facts

Study typeObservational
Enrollment112 (estimated)
Ages18 Years and up
SexAll
SponsorAl-Nahrain University Academic / other
Locations1 site (Baghdad)
Trial IDNCT06729021 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the effectiveness of the Modified Caprini Risk Assessment Score combined with D-Dimer levels in predicting and managing lower extremity venous thrombosis (LEVT) among patients undergoing cardiothoracic surgery in Baghdad. Participants will undergo risk assessments and D-Dimer testing during their hospital stay, with subsequent monitoring for LEVT incidence and related complications. The study seeks to determine if the combined use of these tools enhances predictive accuracy compared to using them separately.

Who should consider this trial

Good fit: Ideal candidates include inpatients undergoing cardiothoracic surgery with a hospital stay of more than three days.

Not a fit: Patients with preexisting venous thrombosis, severe coagulopathy, or those currently receiving anticoagulation therapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved prevention and management strategies for lower extremity venous thrombosis in cardiothoracic surgery patients.

How similar studies have performed: While the approach of using risk assessment tools is common, the specific combination of the Modified Caprini Score and D-Dimer in this context is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Inpatients with a hospital stay over 3 days
* Written informed consent obtained from patients or their legal guardians.
* Availability for postoperative follow-up to assess outcomes like LEVT development or related complications.

Exclusion Criteria:

* Preexisting LEVT or Pulmonary Embolism: Diagnosed before the index surgery.
* Severe Coagulopathy: Patients with inherited or acquired bleeding disorders (e.g., hemophilia, advanced liver disease).
* receiving any anticoagulation therapy for any reason.
* patients who did not undergo a postoperative D-dimer test.
* Incomplete Data: missing essential clinical or laboratory data for Modified Caprini Score calculation or D-Dimer measurement.
* Pregnancy: pregnant women or those within six weeks postpartum.
* Noncompliance: Patients unwilling or unable to adhere to study follow-up protocols.

Where this trial is running

Baghdad

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions DVT - Deep Vein ThrombosisCaprini ScoreD-DimerDVT
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.