Evaluating right ventricular function during general anesthesia

Prediction of TAPSE/PASP Ratio for Hypotension Due to General Anesthesia Induction

Observational Aydin Adnan Menderes University · NCT06414811

This study is testing how well the right side of the heart works during general anesthesia to see if it can help predict low blood pressure in patients having surgery.

Quick facts

Study typeObservational
Enrollment52 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorAydin Adnan Menderes University Academic / other
Locations1 site (Aydin)
Trial IDNCT06414811 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the risk of hypotension in patients undergoing general anesthesia by measuring right ventricular function using TAPSE and PASP parameters. Patients aged 18-75, who are hemodynamically stable and scheduled for surgery, will undergo transthoracic echocardiography before anesthesia induction. Hemodynamic parameters will be monitored closely after induction to identify those who experience significant drops in blood pressure. The study will categorize patients into groups based on the occurrence of hypotension during the procedure.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18-75 with ASA Physical Status 1-3 who are scheduled for surgery.

Not a fit: Patients who are pregnant, have severe pulmonary hypertension, or are classified as ASA Physical Status IV or V may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify patients at risk for hypotensive events during surgery, potentially improving perioperative management and outcomes.

How similar studies have performed: While the specific approach of using TAPSE and PASP in this context may be novel, similar studies have shown the importance of monitoring right ventricular function in surgical settings.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Written informed consent;
2. 18-75 years old
3. ASA Physical Status 1-3;
4. Patients planned for surgery

Exclusion Criteria:

1. The patient is pregnant
2. After cardiac surgery
3. Severe pulmonary hypertension
4. Severe valve disease
5. Hypertrophic or dilated cardiomyopathy
6. Presence of acute myocardial infarction
7. Patients with severe visual or hearing impairment/disability
8. ASA physical status IV or V
9. Ischemic heart disease, conduction disorder.

Where this trial is running

Aydin

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HypotensionTAPSEPASPGENERAL ANESTHESİA
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.