Evaluating results of knee cartilage transplants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the clinical and imaging outcomes of fresh osteochondral allograft transplantation in patients with large osteochondral defects in the knee. It involves a prospective, patient-centered approach where participants will be monitored from baseline to 15 months post-surgery, using various patient-reported outcome measures and imaging techniques like MRI and CT. The study will also explore variations based on additional factors such as age, sex, and other demographic information.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients undergoing cartilage repair with fresh osteochondral allograft transplantation for large focal full-thickness chondral and osteochondral defects (\>2 cm2) on the tibial plateau, femoral condyles, trochlea and/or patella Bipolar lesions are included.

Exclusion Criteria:

* BMI\> 30 kg / m2
* Systemic inflammatory diseases
* Inflammatory arthritis
* Advanced osteoarthritis
* Tricompartmental degenerative process
* Active infection
* Patients who are unable to provide written informed consent.

Where it's running

• Hospital de la Santa Creu i Sant Pau
  Barcelona, Catalonia, Spain Recruiting

Study contacts

• Principal investigator: Pablo Gelber — Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
• Study coordinator: Àlex Grau Blanes
• Email: agraub@santpau.cat
• Phone: +34935537031

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Reconstruction of knee osteochondral defects with autologous cartilage or collagen matrix: clinical and MRI outcomes

  This project will test whether autologous cartilage transplants or collagen knee matrices help adults with osteochondral knee defects and how the repair looks on MRI.

  Recruiting Versailles Hospital · Le Chesnay · NCT03908931

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.