Evaluating recovery after knee surgery with adductor canal block analgesia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study assesses post-operative recovery in patients undergoing unilateral prosthetic knee surgery by evaluating their eligibility for early discharge based on specific recovery criteria. It is a monocentric, interventional, prospective, randomized study with two parallel groups and a single-blind design. Patients will be monitored post-operatively at various intervals to determine their recovery progress and discharge readiness. The study aims to enhance recovery protocols and improve patient outcomes following knee surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient with a score "American Society of Anesthesiologists" I to III;
* Patient undergoing initial unilateral prosthetic knee replacement surgery for osteoarthritis;
* Patient eligible for analgesia by block of the adductor canal associated with additional infiltration;
* Patient accepting to follow the enhanced recovery program after surgery;
* Patient who signed an informed consent form to participate in the study.

Exclusion Criteria:

* Patient with a known allergy to a study product;
* Patient having undergone previous surgery with a prosthesis on the knee to be operated on;
* Patient with morbid obesity (Body Mass Index \> 40);
* Patient with a pre-existing inability to walk;
* Patient with a history of chronic neuropathic pain in the leg undergoing surgery;
* Patient with heart failure with impaired ejection fraction;
* Patient with a history of drug addiction;
* Patient chronically taking level III analgesics;
* Patient taking gabapentin or pregabalin chronically;
* Patient with severe renal or hepatic impairment;
* Patient with a high level of dependence, defined by level 1 or 2 of the Iso-Ressources Group;
* Protected patient (under legal protection, or deprived of liberty by judicial or administrative decision);
* Patient unable to understand the information related to the study (linguistic, psychological, cognitive reasons, etc.);
* Pregnant or likely to be pregnant (of childbearing age without effective contraception) or breastfeeding;
* Patient participating in another clinical trial, or in a period of exclusion from another clinical trial;
* Patient not benefiting from a social security scheme.

Where it's running

• Hôpital Privé Médipôle
  Villeurbanne, France Recruiting

Study contacts

• Study coordinator: Simon DEVILLEZ, MD
• Email: sdevillez@capio.fr
• Phone: 478940606

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Intra-Articular Allocetra for Knee Osteoarthritis

  This study tests whether injecting Allocetra into the knee can help people with moderate-to-severe knee osteoarthritis compare to a placebo.

  Recruiting at 15 sites Phase 2 Enlivex Therapeutics Ltd. · Longwood, Florida and 16 other locations · NCT07580716

• Cold and compression after total knee replacement

  This tests whether using a cold-compression device after total knee replacement reduces pain compared with standard care for adults with primary osteoarthritis.

  Recruiting Ochsner Health System · New Orleans, Louisiana · NCT07023185

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.