Evaluating recovery after knee surgery with adductor canal block analgesia

Assessment of Recovery After Adductor Canal Block Analgesia Associated Either With Infiltration Between Popliteal Artery and Posterior Capsule, or With Surgical Peri-articular Infiltration for Patients Treated by Improved Recovery Program

This study tests if using a specific pain relief method after knee surgery helps patients recover faster and go home sooner.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 130 (estimated)
• Ages: 18 Years to 80 Years
• Sex: All
• Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche (Academic / other)
• Locations: 1 site (Villeurbanne)
• Trial ID: NCT05715645 on ClinicalTrials.gov

What this trial studies

This study assesses post-operative recovery in patients undergoing unilateral prosthetic knee surgery by evaluating their eligibility for early discharge based on specific recovery criteria. It is a monocentric, interventional, prospective, randomized study with two parallel groups and a single-blind design. Patients will be monitored post-operatively at various intervals to determine their recovery progress and discharge readiness. The study aims to enhance recovery protocols and improve patient outcomes following knee surgery.

Who should consider this trial

Good fit: Ideal candidates are patients undergoing initial unilateral prosthetic knee replacement surgery for osteoarthritis who meet specific health criteria.

Not a fit: Patients with previous knee surgeries, severe obesity, or chronic pain conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to faster recovery times and earlier hospital discharge for patients undergoing knee surgery.

How similar studies have performed: Other studies have shown promising results with enhanced recovery protocols in orthopedic surgeries, suggesting potential success for this approach.

Eligibility criteria

Inclusion Criteria:

* Patient with a score "American Society of Anesthesiologists" I to III;
* Patient undergoing initial unilateral prosthetic knee replacement surgery for osteoarthritis;
* Patient eligible for analgesia by block of the adductor canal associated with additional infiltration;
* Patient accepting to follow the enhanced recovery program after surgery;
* Patient who signed an informed consent form to participate in the study.

Exclusion Criteria:

* Patient with a known allergy to a study product;
* Patient having undergone previous surgery with a prosthesis on the knee to be operated on;
* Patient with morbid obesity (Body Mass Index \> 40);
* Patient with a pre-existing inability to walk;
* Patient with a history of chronic neuropathic pain in the leg undergoing surgery;
* Patient with heart failure with impaired ejection fraction;
* Patient with a history of drug addiction;
* Patient chronically taking level III analgesics;
* Patient taking gabapentin or pregabalin chronically;
* Patient with severe renal or hepatic impairment;
* Patient with a high level of dependence, defined by level 1 or 2 of the Iso-Ressources Group;
* Protected patient (under legal protection, or deprived of liberty by judicial or administrative decision);
* Patient unable to understand the information related to the study (linguistic, psychological, cognitive reasons, etc.);
* Pregnant or likely to be pregnant (of childbearing age without effective contraception) or breastfeeding;
* Patient participating in another clinical trial, or in a period of exclusion from another clinical trial;
* Patient not benefiting from a social security scheme.

Where this trial is running

Villeurbanne

• Hôpital Privé Médipôle — Villeurbanne, France (Recruiting)

Study contacts

• Study coordinator: Simon DEVILLEZ, MD

Conditions Unilateral Primary Osteoarthritis of Knee