Evaluating quality of life in patients with difficult-to-treat basal cell carcinoma after surgery

Assessment of Quality of Life in Patients Undergoing Surgery for Difficult-to-treat Basal Cell Carcinoma of the Face in Stage IIA or IIIB According to the European Association of Dermato-Oncology Classification.

Observational Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT06448936

This study looks at how surgery affects the daily lives and well-being of people with hard-to-treat basal cell carcinoma on their face.

Quick facts

Study typeObservational
Enrollment750 (estimated)
Ages18 Years and up
SexAll
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other
Drugs / interventionsradiation
Locations1 site (Roma)
Trial IDNCT06448936 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess how surgical treatment affects the quality of life in patients with stage IIA and IIIB difficult-to-treat basal cell carcinoma located on the face. By utilizing patient-reported outcome measures, the study will gather data on the impact of surgery on daily living and overall well-being. Participants will complete questionnaires to provide insights into their experiences and the factors influencing their quality of life post-surgery.

Who should consider this trial

Good fit: Ideal candidates are patients diagnosed with stage IIA or IIIB difficult-to-treat basal cell carcinoma on the face who can communicate in Italian.

Not a fit: Patients with inoperable or metastatic basal cell carcinoma or those with psychiatric disorders that hinder compliance may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into how surgical interventions can improve the quality of life for patients with challenging facial basal cell carcinoma.

How similar studies have performed: While this approach is observational, similar studies have shown that surgical treatment can significantly impact quality of life in cancer patients, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical or histological diagnosis of difficult-to-treat basal cell carcinoma (DTT-BCC) classified as stage IIA or IIIB according to the EADO classification.
* Tumor location: face.
* Intervention: surgical treatment of facial stage IIA and IIIB difficult-to-treat basal cell carcinoma.
* Sufficient knowledge of spoken and written Italian by the patient.

Exclusion Criteria:

* Known psychiatric or substance abuse disorders that may interfere with cooperation and compliance with trial requirements.
* Inoperable or metastatic difficult-to-treat basal cell carcinoma.
* Contraindications to surgery related to the patient's condition.
* Previous radiation therapy involving the field of the target lesion.

Where this trial is running

Roma

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Basal Cell Carcinoma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.