Evaluating quality of life after surgery for diverticulitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the quality of life outcomes in patients with acute complicated and chronic recurrent left-sided diverticulitis. Patients will be randomized into two groups: one receiving early left hemicolectomy within 7 to 10 days of admission, and the other undergoing elective resection 6 to 8 weeks after initial treatment. Quality of life will be assessed using standardized scoring systems, including the Gastrointestinal Quality of Life Index and the Short-form 36 Score, at various points post-surgery. The study aims to determine the impact of timing of surgery on patient recovery and overall well-being.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Informed consent to participate in the study
* CDD Type 2a, 2b: acute complicated left-sided diverticulitis
* CDD Type 3b: relapsing diverticulitis without complications (\>2 episodes within 2 years)
* Acute presentation
* Inflammation located in the left-sided colon
* Inflammation is CT proven or ultrasound confirmed from experienced radiologists

Exclusion Criteria:

* \< 18 years
* Pregnancy
* BMI \> 55kg/m2
* Current colorectal carcinoma in the left-sided colon
* Oral and/or intravenous corticosteroid
* Ongoing chemotherapy
* Status post left hemicolectomy
* Patients who cannot take care of themselves at home or are unable to follow instructions
* Patients who are not fit for surgery (anesthesia, expert knowledge from specialists) and will not benefit from surgery

Where it's running

• Ordensklinikum Elisabethinen Linz
  Linz, Austria, Austria Recruiting
• Krankenhaus Barmherzige Schwestern Linz
  Linz, Upper Austria, Austria Recruiting
• Kepler University Hospital
  Linz, Upper Austria, Austria Recruiting
• Universitätsklinikum Mannheim
  Mannheim, Mannheim, Germany Not yet recruiting

Study contacts

• Principal investigator: Andreas Shamiyeh, Dr. — Kepler University Hospital Linz
• Study coordinator: Sandra Raab, Dr.
• Email: sandra.raab@kepleruniklinikum.at
• Phone: +43 (0)5 7680 83 - 78470

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• MBK-01 intestinal microbiota capsules to prevent recurrent sigmoid diverticulitis

  This trial will test whether oral MBK-01 intestinal microbiota capsules can reduce repeat episodes in adults who have had three or more episodes of left or sigmoid diverticulitis in the past three years.

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• Elective sigmoid resection for recurrent diverticulitis: does it help bowel function and quality of life?

  This study looks at whether elective sigmoid surgery improves bowel function and quality of life for people with recurring uncomplicated sigmoid diverticulitis who may or may not need surgery.

  Recruiting University Hospital, Basel, Switzerland · Basel · NCT03994978

• Anastomotic bleeding after double-stapled colorectal surgery linked to stapler spike position

  This project will see if placing the stapler spike on the mesenteric versus the opposite side affects early rectal bleeding in adults having double-stapled colorectal anastomoses for cancer or diverticulitis.

  Recruiting Kepler University Hospital · Linz · NCT07506005

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.