Evaluating pre-operative therapy effects in breast cancer
Official title: The Effect of Pre-operative Therapy on Response and Survival in Breast Cancer
Run by RenJi Hospital · NCT05621564 · Data updated 2026-11-12
This study is testing how different pre-surgery treatments for breast cancer affect recovery and survival in women who are about to start therapy.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 6032 (estimated) |
| Sponsor | RenJi Hospital Academic / other |
| Locations | 1 site (Shanghai) |
| Status | Recruiting |
| Started | November 1, 2022 |
| Main results expected | November 2030 |
| Study ends | November 2030 |
| Registry record updated | August 4, 2026 |
| Trial ID | NCT05621564 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are females aged 18 and older with histologically confirmed primary breast cancer who plan to receive pre-operative therapy.
✕Probably not a fit
Patients with a history of neurological or psychological diseases or those deemed unsuitable for participation by investigators may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the impact of pre-operative therapy on response rates and survival outcomes in patients with breast cancer. It will analyze both prospective and retrospective data to compare the effectiveness of different pre-operative regimens based on patients' clinicopathological characteristics. The study will include women aged 18 and older who have been histologically confirmed to have primary breast cancer and are scheduled to receive pre-operative therapy.
Why it matters
Potential benefit: If successful, this study could provide insights into optimizing pre-operative treatment strategies for breast cancer, potentially improving patient outcomes.
How similar studies have gone: Other studies have explored pre-operative therapies in breast cancer, showing varying degrees of success, indicating that this approach has been tested but may still hold novel insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female, Aged ≥18 years * Histologically confirmed primary breast cancer * Plan to receive pre-operative therapy * Adequate organ function Exclusion Criteria: * History of neurological or psychological disease, including epilepsy or dementia * Not suitable to participate in this study judged by investigators
Where it's running
-
Renji Hospital, School of Medicine, Shanghai Jiaotong University
Shanghai, China Recruiting
Study contacts
- Study coordinator: Wenjin Yin
- Email: yinwenjin@renji.com
- Phone: 86(21)68385569
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.