Evaluating pre-operative therapy effects in breast cancer
The Effect of Pre-operative Therapy on Response and Survival in Breast Cancer
This study is testing how different pre-surgery treatments for breast cancer affect recovery and survival in women who are about to start therapy.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 488 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | RenJi Hospital Academic / other |
| Locations | 1 site (Shanghai) |
| Trial ID | NCT05621564 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the impact of pre-operative therapy on response rates and survival outcomes in patients with breast cancer. It will analyze both prospective and retrospective data to compare the effectiveness of different pre-operative regimens based on patients' clinicopathological characteristics. The study will include women aged 18 and older who have been histologically confirmed to have primary breast cancer and are scheduled to receive pre-operative therapy.
Who should consider this trial
Good fit: Ideal candidates for this study are females aged 18 and older with histologically confirmed primary breast cancer who plan to receive pre-operative therapy.
Not a fit: Patients with a history of neurological or psychological diseases or those deemed unsuitable for participation by investigators may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into optimizing pre-operative treatment strategies for breast cancer, potentially improving patient outcomes.
How similar studies have performed: Other studies have explored pre-operative therapies in breast cancer, showing varying degrees of success, indicating that this approach has been tested but may still hold novel insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female, Aged ≥18 years * Histologically confirmed primary breast cancer * Plan to receive pre-operative therapy * Adequate organ function Exclusion Criteria: * History of neurological or psychological disease, including epilepsy or dementia * Not suitable to participate in this study judged by investigators
Where this trial is running
Shanghai
- Renji Hospital, School of Medicine, Shanghai Jiaotong University — Shanghai, China (Recruiting)
Study contacts
- Study coordinator: Wenjin Yin
- Email: yinwenjin@renji.com
- Phone: 86(21)68385569
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.