Evaluating post-surgery radiation treatment for Dupuytren's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational pilot study aims to assess the effectiveness of a treatment pathway for Dupuytren's disease, which includes surgical contracture release followed by radiation therapy. Participants will receive a standard treatment involving limited fasciectomy, PNA, or CCH injection, followed by a series of radiation treatments. Data will be collected on participants' symptoms and hand function at various intervals to evaluate the clinical outcomes of the treatment. The study seeks to substantiate clinicians' impressions of patient improvement with scientific evidence.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnoses of Dupuytren's disease
* English-speaking

Exclusion Criteria:

\- Patients with Dupuytren's disease who are not currently seeking treatment

Where it's running

• University of Minnesota
  Minneapolis, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Leslie Chang — University of Minnesota
• Study coordinator: Leslie Chang
• Email: dupuytrensumn@umn.edu
• Phone: 612-273-6014

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• CNT201 collagenase injection for Dupuytren’s: safety and signals of efficacy in adults

  A randomized, placebo-controlled study will test CNT201 injections to see if they are safe and help improve finger contractures in adults with Dupuytren’s disease.

  Recruiting Phase 1/2 Connext · Kippa-Ring, Queensland · NCT07640425

• Treatment options for Dupuytren's contracture

  This study is testing whether adding a corticosteroid injection to a needle treatment helps people with Dupuytren's contracture move their fingers better.

  Recruiting Phase 4 Regionshospitalet Silkeborg · Silkeborg · NCT05440240

• Evaluating night splinting after needle fasciotomy for Dupuytren's contracture

  This study is testing if wearing a night splint after a needle procedure for Dupuytren's contracture can help prevent the condition from coming back compared to just physical therapy alone.

  Recruiting at 3 sites Uppsala University · Falun, Dalarna County and 2 other locations · NCT05300893

• Evaluating a new ultrasound-guided technique for Dupuytren's contracture

  This study is testing a new ultrasound-guided procedure to see if it can safely improve hand function for people with Dupuytren's contracture while causing fewer problems than traditional surgery.

  Recruiting Mansoura University Hospital · Al Mansurah, Dakahlia Governorate · NCT06788847

• Using radiation therapy to prevent Dupuytren's contracture recurrence after treatment

  This study is testing if targeted radiation therapy can help prevent Dupuytren's contracture from coming back after treatment in people aged 45 and older.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06330545

• Treatment for early Dupuytren's disease using vitamin E cream

  This study is testing if using vitamin E cream can help people with early Dupuytren's disease stop their fingers from getting worse.

  Recruiting Phase 2 Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams-Brabant · NCT06321991

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.