Evaluating post-surgery radiation treatment for Dupuytren's disease
Efficacy of Post-contracture Release Radiation for the Treatment of Dupuytren's Disease
This study is testing whether adding radiation treatment after surgery for Dupuytren's disease can help improve hand function and reduce symptoms for patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Minnesota Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Minneapolis, Minnesota) |
| Trial ID | NCT04122313 on ClinicalTrials.gov |
What this trial studies
This observational pilot study aims to assess the effectiveness of a treatment pathway for Dupuytren's disease, which includes surgical contracture release followed by radiation therapy. Participants will receive a standard treatment involving limited fasciectomy, PNA, or CCH injection, followed by a series of radiation treatments. Data will be collected on participants' symptoms and hand function at various intervals to evaluate the clinical outcomes of the treatment. The study seeks to substantiate clinicians' impressions of patient improvement with scientific evidence.
Who should consider this trial
Good fit: Ideal candidates for this study are English-speaking individuals diagnosed with Dupuytren's disease who are actively seeking treatment.
Not a fit: Patients with Dupuytren's disease who are not currently seeking treatment will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide evidence-based support for a treatment approach that may improve outcomes for patients with Dupuytren's disease.
How similar studies have performed: While this approach is based on established treatment protocols, the specific observational nature of this study may provide new insights into its effectiveness.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnoses of Dupuytren's disease * English-speaking Exclusion Criteria: \- Patients with Dupuytren's disease who are not currently seeking treatment
Where this trial is running
Minneapolis, Minnesota
- University of Minnesota — Minneapolis, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Leslie Chang — University of Minnesota
- Study coordinator: Leslie Chang
- Email: dupuytrensumn@umn.edu
- Phone: 612-273-6014
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.