Evaluating Pediatric Patients with Genetic Disorders

Evaluation of Patients With Genetic Disorders

National Institutes of Health Clinical Center (CC) · NCT02769949

This study is looking for children with genetic disorders to help clinic staff learn more while also providing them with medical check-ups and possible treatments.

Quick facts

Study typeObservational
Enrollment5000 (estimated)
Ages1 Year to 99 Years
SexAll
SponsorNational Institutes of Health Clinical Center (CC) (nih)
Locations1 site (Bethesda, Maryland)
Trial IDNCT02769949 on ClinicalTrials.gov

What this trial studies

This observational study aims to recruit a diverse group of pediatric patients with known or suspected genetic disorders to provide hands-on experience for clinic staff. Participants will undergo a thorough medical history review, physical examinations, and may have various lab tests and imaging studies performed. The study seeks to generate hypotheses and collect biospecimens for future research while also allowing for clinical evaluations and potential treatments at the NIH. Family members may also be enrolled to provide additional genetic insights.

Who should consider this trial

Good fit: Ideal candidates include children of any age with known or suspected genetic disorders.

Not a fit: Patients with medical, psychiatric, or social conditions that may complicate participation or increase risk may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding and management of genetic disorders in pediatric patients.

How similar studies have performed: Other studies involving genetic evaluations in pediatric populations have shown promise, indicating that this approach could yield valuable insights.

Eligibility criteria

Show full inclusion / exclusion criteria
* INCLUSION CRITERIA:
* Subjects of any age with known or suspected genetic disorder
* For relatives of subjects with a genetic disorder: Subject is a family member of the proband

EXCLUSION CRITERIA:

-Presence of a medical, psychiatric, or social condition which, in the opinion of the investigator, would place undue burden on the subject, NIH resources, or increase risk of participation

Where this trial is running

Bethesda, Maryland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Genetic Disorder, Asperger Disorder, Autism Spectrum Disorder, Fragile X Syndrome, Developmental Delay, Genetics, Metabolic, Dysmorphic Syndromes

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.