Evaluating pain management with ANI during general anesthesia using remimazolam

Performance Evaluation of Analgesia Nociception Index (ANI) in Patients Under General Anaesthesia With Remimazolam: a Prospective Observational Study

Observational Catholic Kwandong University · NCT06432894

This study is testing if a new pain measurement tool can help reduce the amount of opioids needed for patients aged 20-79 having robotic surgery while under general anesthesia with remimazolam.

Quick facts

Study typeObservational
Enrollment30 (estimated)
Ages20 Years to 79 Years
SexAll
SponsorCatholic Kwandong University Academic / other
Locations1 site (Incheon)
Trial IDNCT06432894 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the effectiveness of the Analgesia Nociception Index (ANI) in reducing opioid dosage for patients undergoing general anesthesia with remimazolam. It focuses on patients aged 20-79 scheduled for robotic surgery and evaluates their pain levels during the procedure. The study will monitor the relationship between ANI readings and opioid requirements, potentially leading to improved pain management strategies.

Who should consider this trial

Good fit: Ideal candidates are patients aged 20-79 undergoing robotic surgery under general anesthesia with remimazolam.

Not a fit: Patients with conditions affecting the autonomic nervous system or those experiencing significant preoperative pain may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to reduced opioid use and improved pain management for patients undergoing surgery.

How similar studies have performed: While the use of ANI in pain management is gaining interest, this specific application with remimazolam is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Patients

* aged 20-79 years under general anaesthesia with remimazolam
* scheduled to undergo robotic surgery
* in American Society of Anesthesiologists physical class 1, 2 or 3
* voluntarily agree in writing to participate in this clinical study

Exclusion Criteria:

* Conditions affecting the autonomic nervous system
* other conditions or disease that may cause acute or chronic pain
* the NRS before induction of anesthesia is 1 or over
* When taking medications that may affect the autonomic nervous system
* In other cases where the investigator deems the subject unsuitable for this trial

Where this trial is running

Incheon

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pain MeasurementRemimazolamRemifentanilAnalgesia Nociception Index
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.