Evaluating pain and debris extrusion from different irrigation techniques in dental procedures

Correlation Between Postoperative Pain and Apical Extrusion of Different Irrigation Activation Techniques (Randomized Controlled Trial - an In Vitro Study)

Not applicable Interventional Ain Shams University · NCT06573710

This study is testing different ways to clean teeth during dental procedures to see which method causes less pain and pushes out less debris for patients with irreversible pulpitis.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment32 (estimated)
Ages18 Years to 50 Years
SexAll
SponsorAin Shams University Academic / other
Locations1 site (Cairo)
Trial IDNCT06573710 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to assess the impact of various irrigation activation techniques, including LASER, sonic, ultrasonic, and passive needle irrigation, on postoperative pain and the amount of debris extrusion in patients with irreversible pulpitis. Participants will report their pain levels before and after the procedure at specified intervals. The study will utilize a randomized controlled trial design to compare the effectiveness of these techniques in managing pain and minimizing debris during dental treatments.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18-50 with symptomatic irreversible pulpitis in lower molars.

Not a fit: Patients with uncontrolled health conditions, immunocompromised status, periodontal diseases, calcified canals, or those who are pregnant may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management and treatment outcomes for patients undergoing dental procedures for irreversible pulpitis.

How similar studies have performed: While there have been studies on various irrigation techniques, this specific comparison of LASER, sonic, and ultrasonic methods in relation to postoperative pain and debris extrusion is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age group 18-50 years
* Males and females
* Lower molars with symptomatic irreversible pulpitis without apical periodontitis

Exclusion Criteria:

* Patients with uncontrolled health conditions
* Immunocompromised patients
* Teeth with periodontal diseases
* Teeth with calcified canals
* pregnant patients

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pulpitis - Irreversibleirrigant , ultrasonic, LASER , sonic
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.