Evaluating oxygen therapy during sedation in children

Evaluation of the Efficacy of Oxygen Therapy and Clinical Feasibility of High Flow Nasal Cannula During Moderate and Deep Sedation in Pediatric Patients

Not applicable Interventional Seoul National University Hospital · NCT04852432

This study tests whether giving oxygen through traditional nasal prongs or a high flow nasal cannula helps keep children safe and well-oxygenated during sedation for medical procedures.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment258 (estimated)
AgesN/A to 17 Years
SexAll
SponsorSeoul National University Hospital Academic / other
Locations1 site (Seoul)
Trial IDNCT04852432 on ClinicalTrials.gov

What this trial studies

This study assesses the effectiveness and safety of administering oxygen to pediatric patients undergoing moderate to deep sedation. It compares two methods of oxygen delivery: traditional nasal prongs and high flow nasal cannula. The goal is to determine which method provides better outcomes in terms of oxygenation and overall safety during sedation procedures. The study focuses on children under 18 years old who require sedation for medical procedures.

Who should consider this trial

Good fit: Ideal candidates are children under 18 years old who need moderate to deep sedation for medical procedures.

Not a fit: Patients with respiratory failure, increased intracranial pressure, or other specified conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the safety and efficacy of sedation practices in pediatric patients.

How similar studies have performed: Other studies have explored oxygen therapy in sedation, but this specific comparison of delivery methods is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Children under the age of 18 who undergo moderate-deep sedation

Exclusion Criteria:

* Respiratory failure patients
* Increased intracranial pressure
* Recent massive nasal bleeding
* History of airway surgery
* Complete nasal obstruction
* Pulmonary hypertension
* Skull base fracture

Where this trial is running

Seoul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pediatric Sedation
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.