Evaluating outcomes of unruptured brain arteriovenous malformations using multimodal CT

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the clinical outcomes of patients with unruptured brain arteriovenous malformations (bAVMs) who are managed medically. It utilizes multimodal CT imaging to analyze morphological, structural, and hemodynamic features of bAVMs, exploring their relationship with clinical outcomes. The study also employs deep learning algorithms to develop automated segmentation and prediction models based on imaging data. Patient follow-up will occur at multiple intervals over three years to gather comprehensive clinical information.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with confirmed diagnosis of brain arteriovenous malformations in the brain, basal ganglia, thalamus, corpus callosum, cerebellum and other locations.
2. Patients with no history of previous arteriovenous malformation-related hemorrhage and no arteriovenous malformation-related hemorrhage confirmed by CT examination.
3. Patients with Radiographic examinations completed without any treatment

Exclusion Criteria:

1. Patients with simple arteriovenous fistula.
2. Patients with combined dural arteriovenous fistulas.
3. Arteriovenous malformations occurring in the spinal cord.
4. Pregnant patients were not included in this study.

Where it's running

• Beijing Tiantan Hospital, Capital Medical University
  Beijing, Beijing Municipality, China Recruiting
• Beijing Hospital
  Beijing, Beijing Municipality, China Recruiting
• The First Affiliated Hospital of Zhengzhou University
  Zhengzhou, Henan, China Recruiting
• The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
  Nanjing, Jiangsu, China Recruiting

Study contacts

• Principal investigator: Guosheng Zhou — The First Affiliated Hospital of Zhengzhou University
• Study coordinator: Shaosen Zhang, Doctor
• Email: longyoubafang@hotmail.com
• Phone: +8618611284839

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.