Evaluating outcomes of radiofrequency ablation for benign thyroid nodules
Clinical Outcomes and Quality of Life Measures After Surgical Resection and Radiofrequency Ablation of Benign Thyroid Nodules
This study tests if a new treatment called radiofrequency ablation can help people with bothersome benign thyroid nodules feel better compared to traditional surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Columbia University Academic / other |
| Locations | 1 site (New York, New York) |
| Trial ID | NCT05189314 on ClinicalTrials.gov |
What this trial studies
This observational research aims to assess clinical outcomes and quality of life in patients with symptomatic benign multinodular goiter (MNG) after treatment. Participants will provide access to their medical information before and after undergoing either thyroidectomy or radiofrequency ablation (RFA). The study focuses on the effectiveness of RFA, a minimally invasive technique that induces local thermodestruction to shrink nodules and alleviate symptoms. By comparing outcomes, the study seeks to establish the viability of RFA as an alternative to traditional surgical methods.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older with benign thyroid nodules causing symptoms.
Not a fit: Patients with cardiac arrhythmia or those who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a less invasive treatment option for patients with benign thyroid nodules, potentially reducing complications associated with surgery.
How similar studies have performed: Other studies have shown successful outcomes with radiofrequency ablation for thyroid nodules in various countries, indicating promising potential for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients \>/=18 years old with benign thyroid nodules Exclusion Criteria: * cardiac arrhythmia * pregnancy
Where this trial is running
New York, New York
- Columbia University — New York, New York, United States (Recruiting)
Study contacts
- Principal investigator: Jennifer H Kuo, MD MS — Columbia University
- Study coordinator: Jennifer H Kuo, MD MS
- Email: jhk2029@cumc.columbia.edu
- Phone: 212-305-6969
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.