Evaluating outcomes of neoadjuvant immunotherapy in lung cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the effectiveness and long-term clinical outcomes of various neoadjuvant immunotherapies in patients with non-small cell lung cancer (NSCLC) using real-world data. It seeks to determine the optimal use of immune checkpoint inhibitors as neoadjuvant treatment and identify specific patient subgroups that benefit the most from this therapy. Participants will receive neoadjuvant immunotherapy, and the study will analyze their outcomes to refine treatment strategies for NSCLC management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Histological diagnosis of non-small cell lung cancer (Stage I-IV, International Association for the Study of Lung Cancer staging eighth edition)
2. Patients who have previously undergone immune checkpoint inhibitors as the neoadjuvant treatment;
3. No previous history of malignant tumors and other malignant tumors at the same time, without any anti-tumor treatment;
4. Eastern Cooperative Oncology Group (ECOG) score 0-1, heart, lung, liver, brain and kidney function can tolerate surgery;
5. At least one measurable lesion (RECIST v1.1).

Exclusion Criteria:

1. Patients included in unblinded clinical trials or anti-tumor drug intervention.
2. Radiotherapy or systemic therapy were used for NSCLC patients before the surgery.

Where it's running

• Shugeng Gao
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Shugeng Gao, MD — Cancer Institute and Hospital, Chinese Academy of Medical Sciences
• Study coordinator: Shugeng Gao, MD
• Email: gaoshugeng@cicams.ac.cn
• Phone: 8610-87788177

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.