Clinical trial Recruiting at 1 site Observational Ages 18 to 100 Women only

Evaluating outcomes and side effects of salvage treatment for recurrent breast cancer

Official title: A Prospective Registry Study to Evaluate Oncologic Outcomes and Toxicities of Salvage Treatment in Patients With Locoregionally Recurrent Breast Cancer

Run by Samsung Medical Center · NCT05933733 · Data updated 2026-11-12

This study is testing how well salvage treatments work and what side effects they cause in women with recurring breast cancer that hasn't spread to other parts of the body.

More Breast Cancer trials

Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexWomen only
Enrollment190 (estimated)
SponsorSamsung Medical Center
Academic / other
Drugs / interventionsradiation
Locations1 site (Seoul)
StatusRecruiting
StartedJuly 4, 2023
Main results expectedJuly 2028
Study endsJuly 2033
Registry record updatedJune 29, 2025
Trial IDNCT05933733 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are female patients aged 18 to 100 who have experienced locoregional recurrence of breast cancer after initial definitive treatment.

Probably not a fit

Patients who do not meet the eligibility criteria or are not anticipated to comply with the study protocol may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the clinical outcomes and adverse events associated with salvage treatment in patients experiencing locoregional recurrence of breast cancer. It will evaluate disease status, quality of life, and molecular signatures related to treatment resistance through various assessments, including physical examinations, radiologic evaluations, and patient questionnaires. The study will focus on female patients who have previously undergone definitive treatment for breast cancer and are now facing recurrence without distant metastasis.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into effective salvage treatment strategies and improve quality of life for patients with recurrent breast cancer.

How similar studies have gone: While there have been studies on salvage treatments for breast cancer, this specific observational approach focusing on outcomes and molecular signatures is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Female patients with age 18 to 100.
* Previous standard definitive treatment for initial breast cancer
* Locoregional recurrence without distant metastasis
* Planned salvage treatment for locoregional recurrence
* Informed consent of the participant

Exclusion Criteria:

\- Not anticipated for complying the study protocol

Where it's running

  • Samsung Medical Center
    Seoul, South Korea
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.