Evaluating outcomes after a specific ankle surgery for cartilage repair

Valutazione Dell'Epidemiologia e Dei Risultati Radiografici e Clinici Nel Trattamento Artroscopico Delle Lesioni Osteocondrali Dell'Astragalo Con Tecnica AMIC

Not applicable Interventional I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · NCT03371121

This study tests whether a new ankle surgery that helps repair cartilage can reduce pain and improve movement for people with specific ankle joint problems.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment103 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorI.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio Academic / other
Locations1 site (Milan)
Trial IDNCT03371121 on ClinicalTrials.gov

What this trial studies

This study aims to assess the clinical and radiographic outcomes in patients who have undergone all-arthroscopic autologous matrix induced chondrogenesis (AMIC) for symptomatic osteochondral lesions of the talus. The intervention involves a minimally invasive surgical technique designed to promote cartilage regeneration in the ankle joint. By analyzing patient outcomes post-surgery, the study seeks to determine the effectiveness of this treatment approach in alleviating pain and improving function.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years who have undergone arthroscopic cartilage reconstruction surgery for osteochondral lesions of the talus.

Not a fit: Patients under 18 years or those who have had previous surgery on the affected ankle may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could significantly improve pain relief and functional recovery for patients with talar osteochondral defects.

How similar studies have performed: Other studies have shown promising results with similar arthroscopic techniques for cartilage repair, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age over 18 years
* males and females
* patients underwent arthroscopic cartilage reconstruction surgery with AMIC technique for osteochondral lesions of the talus

Exclusion Criteria:

* age \<18 years at the time of surgery
* patients with previous surgery on the affected ankle

Where this trial is running

Milan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Talar Osteochondral Defect of AnklePainArthroscopy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.