Evaluating one versus two visits for root canal retreatment outcomes
Official title: Clinical and Radiographic Outcome of Endodontic Retreatment in One or Two Visits: A Randomized Controlled Trial.
Run by Universitat Internacional de Catalunya · NCT04527705 · Data updated 2026-11-12
This study is testing whether having a root canal retreatment done in one visit or two visits works better for people with certain dental issues.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 110 (estimated) |
| Sponsor | Universitat Internacional de Catalunya Academic / other |
| Locations | 1 site (Sant Cugat del Vallès, Barcelona) |
| Status | Recruiting |
| Started | September 20, 2018 |
| Main results expected | July 20, 2021 |
| Study ends | July 20, 2031 |
| Registry record updated | August 26, 2020 |
| Trial ID | NCT04527705 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients with a diagnosis of apical periodontitis requiring non-surgical retreatment of single or bi-radicular teeth.
✕Probably not a fit
Patients with systemic diseases, root resorption, or those for whom secondary root canal treatment is not the treatment of choice may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study is a prospective randomized controlled trial that investigates the success rates of non-surgical root canal retreatment performed in either one or two visits for patients with periapical disease. The research aims to follow patients for up to 10 years to assess the effectiveness of each treatment approach. The null hypothesis posits that there will be no significant difference in success rates between the two methods. Participants must provide informed consent and meet specific eligibility criteria related to their dental condition.
Why it matters
Potential benefit: If successful, this study could provide insights into the most effective treatment approach for root canal retreatment, potentially improving patient outcomes.
How similar studies have gone: While similar studies have explored root canal treatments, this specific comparison of one versus two visits is less commonly tested, making it a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients that demonstrate understanding of the study and willingness to participate as evidenced by signing the voluntary informed consent and received a signed and dated copy of the informed consent form. * Understands and is willing to comply with all study procedures and restrictions. * Not presence of clinically significant and relevant abnormalities of clinical history or oral examination. * Retreatment cases due to an endodontic failure. * Diagnosis of apical periodontitis. * Single or bi-radicular teeth. Exclusion Criteria: * General: Patients with systemic diseases, diabetes, immunocompromised and pregnant women, or any clinically significant or relevant oral abnormalities. * Specific: root resorption, root fractures, impossibility of restoration and cases were secondary root canal treatment is not the treatment of choice.
Where it's running
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Universitat Internacional de Catalunya
Sant Cugat del Vallès, Barcelona, Spain Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.