Evaluating non-surgical treatments for peri-implantitis

Clinical and Biochemical Evaluation of the Efficacy of Different Non-Surgical Peri-implantitis Treatment Approaches

Not applicable Interventional Hacettepe University · NCT06849856

This study is testing whether a new air abrasion cleaning method or traditional plaque removal works better for treating gum inflammation around dental implants.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorHacettepe University Academic / other
Locations1 site (Ankara)
Trial IDNCT06849856 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of different non-surgical treatment approaches for peri-implantitis, a common inflammatory condition affecting dental implants. The research focuses on comparing traditional mechanical plaque removal methods using titanium curettes with a novel air abrasion system that utilizes abrasive powder and compressed air for cleaning implant surfaces. The goal is to determine which method provides better long-term clinical outcomes in managing peri-implant diseases. Participants will be monitored for their response to these treatments over a specified period.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-65 with at least one dental implant showing probing depths of 6 mm or deeper and no periodontal treatment in the last 6 months.

Not a fit: Patients with systemic diseases affecting the periodontium, smokers, or those with significant bone loss around their implants may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more effective non-surgical treatments for peri-implantitis, improving patient outcomes and implant longevity.

How similar studies have performed: While traditional methods have shown limited long-term success, the use of air abrasion systems is a novel approach that has not been extensively tested in this context.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Who have not received any periodontal treatment in the last 6 months,
2. Who have not used any medication (antibiotics, anti-inflammatory drugs, antibacterial mouthwashes, corticosteroids) that could affect the results of the study in the last 3 months,
3. Who have at least one implant with a probing depth of 6 mm or deeper in one or more areas in the mouth, and the implant in question has been in function for at least 1 year,
4. Between the ages of 18-65,
5. Individuals who approve the informed consent form will be included in the study.

Exclusion Criteria:

Individuals who:

1. have a systemic disease that may affect the periodontium,
2. regularly use medication that may affect the periodontium,
3. smoke,
4. are pregnant or lactating,
5. are sensitive to chlorhexidine,
6. have more than 50% bone loss around their current implant(s),
7. do not approve the informed consent form will be excluded from the study.

Where this trial is running

Ankara

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Periimplantitisperi-implantitis, airflow
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.