Evaluating non-invasive methods for predicting kidney failure in patients with liver complications
Non-invasive Evaluation of the Predictive Value of CEUS and SWE in Patients With and Without TIPS With ACLF, Renal Failure and Hepatorenal Syndrome
This study is testing if new non-invasive methods can help predict kidney failure in patients with liver problems, both with and without a specific treatment called TIPS.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | University Hospital, Bonn Academic / other |
| Locations | 1 site (Bonn) |
| Trial ID | NCT04446858 on ClinicalTrials.gov |
What this trial studies
This study evaluates the prognostic value of non-invasive assessments in patients experiencing acute-on-chronic liver failure (ACLF) and renal failure, both with and without the intervention of transjugular intrahepatic portosystemic shunt (TIPS). It involves a structured follow-up program where clinical and laboratory data are collected and analyzed to identify potential predictive markers. The study aims to enhance understanding of kidney failure progression in the context of liver disease using advanced imaging techniques and biomarkers.
Who should consider this trial
Good fit: Ideal candidates include patients with portal hypertension and kidney failure.
Not a fit: Patients without kidney failure or portal hypertension will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved prognostic tools for managing kidney failure in patients with liver complications.
How similar studies have performed: Other studies have explored similar non-invasive approaches, but the specific combination of techniques in this study is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients with portal hypertension and kidney failure Exclusion Criteria: * no consent, no kidney failure, no portal hypertension
Where this trial is running
Bonn
- University Hospital Bonn — Bonn, Germany (Recruiting)
Study contacts
- Principal investigator: Michael Praktiknjo, MD — University Hospital, Bonn
- Study coordinator: Michael Praktiknjo, MD
- Email: michael.praktiknjo@ukbonn.de
- Phone: +49(0)228-287 15770
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.