Evaluating non-invasive imaging techniques for blood flow assessment
A Pilot Study to Evaluate Multi-Spectral Imaging (MI) and Laser Speckle Imaging (LSI) and Multiphoton Microscopy (MPM) During Vascular Occlusion
University of California, Irvine · NCT01484730
This study is testing new non-invasive imaging techniques to see how well they can measure blood flow changes in the skin when a pressure cuff is applied.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of California, Irvine (other) |
| Locations | 1 site (Irvine, California) |
| Trial ID | NCT01484730 on ClinicalTrials.gov |
What this trial studies
This research evaluates the performance of non-invasive imaging modalities, specifically Multi-Spectral Imaging and Laser Speckle Imaging, to assess skin blood flow dynamics during vascular occlusion. A pressure cuff will be applied to stimulate changes in blood flow, allowing researchers to measure vascular conditions ranging from ischemia to hyperemia. The study aims to establish the feasibility of these imaging technologies in detecting variations in hemoglobin concentration and blood flow in the skin.
Who should consider this trial
Good fit: Ideal candidates include adult males and females aged 18 years and older with no pregnancy status.
Not a fit: Patients under 18 years of age or those who are pregnant will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance non-invasive diagnostic techniques for assessing vascular conditions, leading to better patient management.
How similar studies have performed: While this approach is innovative, similar imaging techniques have shown promise in other studies, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male and female adult 18 years and older Exclusion Criteria: * Younger than 18 years of age * Pregnant women
Where this trial is running
Irvine, California
- Beckman Laser Institute and Medical Clinic — Irvine, California, United States (RECRUITING)
Study contacts
- Principal investigator: Anthony Durkin, PhD — University of California, Irvine
- Study coordinator: Gordon Kennedy, PhD
- Email: gordon.kennedy@uci.edu
- Phone: 949-824-4713
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Abnormal Vascular Flow