Evaluating non-invasive imaging techniques for blood flow assessment
Official title: A Pilot Study to Evaluate Multi-Spectral Imaging (MI) and Laser Speckle Imaging (LSI) and Multiphoton Microscopy (MPM) During Vascular Occlusion
Run by University of California, Irvine · NCT01484730 · Data updated 2026-11-12
This study is testing new non-invasive imaging techniques to see how well they can measure blood flow changes in the skin when a pressure cuff is applied.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | University of California, Irvine Academic / other |
| Locations | 1 site (Irvine, California) |
| Status | Recruiting |
| Started | November 2011 |
| Main results expected | August 2026 |
| Study ends | August 2028 |
| Registry record updated | December 10, 2025 |
| Trial ID | NCT01484730 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adult males and females aged 18 years and older with no pregnancy status.
✕Probably not a fit
Patients under 18 years of age or those who are pregnant will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This research evaluates the performance of non-invasive imaging modalities, specifically Multi-Spectral Imaging and Laser Speckle Imaging, to assess skin blood flow dynamics during vascular occlusion. A pressure cuff will be applied to stimulate changes in blood flow, allowing researchers to measure vascular conditions ranging from ischemia to hyperemia. The study aims to establish the feasibility of these imaging technologies in detecting variations in hemoglobin concentration and blood flow in the skin.
Why it matters
Potential benefit: If successful, this study could enhance non-invasive diagnostic techniques for assessing vascular conditions, leading to better patient management.
How similar studies have gone: While this approach is innovative, similar imaging techniques have shown promise in other studies, suggesting potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male and female adult 18 years and older Exclusion Criteria: * Younger than 18 years of age * Pregnant women
Where it's running
-
Beckman Laser Institute and Medical Clinic
Irvine, California, United States Recruiting
Study contacts
- Principal investigator: Anthony Durkin, PhD — University of California, Irvine
- Study coordinator: Gordon Kennedy, PhD
- Email: gordon.kennedy@uci.edu
- Phone: 949-824-4713
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.