Evaluating new diagnostic markers for complicated appendicitis

New Diagnostic Markers In Dignosis Of Complicated Appendix

Not applicable Interventional Sohag University · NCT06102239

This study is testing if certain blood markers can help doctors better identify complications in patients with appendicitis who need surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages10 Years to 40 Years
SexAll
SponsorSohag University Academic / other
Locations1 site (Sohag)
Trial IDNCT06102239 on ClinicalTrials.gov

What this trial studies

This study investigates the efficacy of hyperbilirubinemia and hyponatremia as diagnostic indicators for complicated appendicitis. Patients admitted for acute appendicitis will undergo surgery, and their bilirubin, sodium, and C-reactive protein levels will be measured post-operatively. The goal is to determine if these markers can help identify complications such as perforation more effectively. The findings could lead to improved diagnostic protocols for acute appendicitis.

Who should consider this trial

Good fit: Ideal candidates are patients admitted for acute appendicitis who will undergo surgical intervention.

Not a fit: Patients with liver disease, pregnancy, or other specified exclusions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the accuracy of diagnosing complicated appendicitis, potentially reducing the risk of severe complications.

How similar studies have performed: While there is limited information on similar studies, the approach of using biochemical markers for diagnosis has shown promise in other conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* all patient admitted for acute appendicitis underwent surgery and post operativly confirmed histopathology of acute appendicitis

Exclusion Criteria:

* patient with liver disease Liver transplantation Chronic alcoholism Congental biliary disease Pregnancy Appendicular neoplasm Hemolytic disease Hepatocellular carcinoma

Where this trial is running

Sohag

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Complicated Appendicitis
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.