Evaluating neuroimaging techniques in acute stroke patients
Predictive Value of Brainomix Software CT Evaluation for Final Outcome in Patients With Acute Non-lacunar Stroke
This study is testing if certain brain scans can help predict how well people with acute stroke will recover after receiving treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital Ostrava Academic / other |
| Locations | 1 site (Ostrava, Moravian-Silesian Region) |
| Trial ID | NCT05864495 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the predictive value of various CT parameters, including e-ASPECTS and collateral vessel status, on the functional outcomes of patients with acute ischemic non-lacunar stroke after receiving recanalization treatments. Conducted across multiple stroke centers in the Czech Republic, the study includes patients treated with intravenous thrombolysis or mechanical thrombectomy. Follow-up imaging will be performed to accurately measure ischemic lesion volume and its impact on recovery at three months, using advanced imaging software for analysis.
Who should consider this trial
Good fit: Ideal candidates are adults with acute ischemic stroke treated within 12 hours of onset and a pre-event modified Rankin Scale score of 4 or lower.
Not a fit: Patients with pre-existing severe disability (mRS > 4) or those with acute hemorrhage will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of neuroimaging's role in predicting recovery outcomes for stroke patients.
How similar studies have performed: Other studies have shown promise in using neuroimaging to predict outcomes in stroke patients, indicating a potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Acute ischemic stroke within 12 hours of onset, treated with intravenous thrombolysis and/or mechanical thrombectomy or conservatively. * Unknown time of onset of ischemic stroke. * Wake-up stroke (with symptoms of stroke since awakening). Exclusion Criteria: * Pre-event modified Rankin Scale (mRS) score \> 4 points. * Acute haemorrhagia or other NCCT finding excluding dg. ischemic stroke.
Where this trial is running
Ostrava, Moravian-Silesian Region
- University Hospital Ostrava — Ostrava, Moravian-Silesian Region, Czechia (Recruiting)
Study contacts
- Principal investigator: Michal Bar, Assoc.Prof.,MD,Ph.D. — University Hospital Ostrava
- Study coordinator: Jiří Hynčica
- Email: jiri.hyncica@fno.cz
- Phone: 0042059737
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.