Evaluating lung ultrasound for diagnosing acute respiratory distress syndrome

Validity of Lung Ultrasound in Diagnosis of Acute Respiratory Distress Syndrome and Prediction of Successful Weaning From Mechanical Ventilation in Those Patients

This study is testing if lung ultrasound can accurately diagnose acute respiratory distress syndrome in patients compared to traditional imaging methods like CT scans and X-rays.

Quick facts

• Study type: Observational
• Enrollment: 57 (estimated)
• Ages: 19 Years to 70 Years
• Sex: All
• Sponsor: Zagazig University (Government)
• Locations: 1 site (Zagazig, El Sharkia)
• Trial ID: NCT05886556 on ClinicalTrials.gov

What this trial studies

This study aims to assess the effectiveness of lung ultrasound in diagnosing acute respiratory distress syndrome (ARDS) compared to traditional imaging methods like CT chest and chest radiographs. A total of 57 patients diagnosed with ARDS will be evaluated using lung ultrasound and chest radiographs to determine their sensitivity against the CT chest, which serves as the gold standard. The study will also explore the potential of lung ultrasound in predicting successful weaning from mechanical ventilation. The findings could provide insights into a less invasive diagnostic approach for ARDS.

Who should consider this trial

Good fit: Ideal candidates include patients with suspected acute respiratory distress syndrome who are hemodynamically stable.

Not a fit: Patients with traumatic lung injuries, pneumothorax, or other conditions that interfere with ultrasound examination may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to a more accessible and less invasive method for diagnosing ARDS, improving patient outcomes.

How similar studies have performed: While the use of lung ultrasound in various respiratory conditions has shown promise, this specific approach for ARDS diagnosis is relatively novel and has not been extensively tested.

Eligibility criteria

Inclusion Criteria:

Patients or legal guardian's consent .All patients with suspicious criteria of acute respiratory distress syndrome .Hemodynamically stable in the absence or minimal of vasopressors.

Exclusion Criteria:

Pregnant women. patients with traumatic lung injury or pneumothorax. surgical dressings over the right lower rib cage which would preclude ultrasound examination. presence of ascites. presence of lung collapse, fibrosis, or pleural effusion.

-presence of any mass or mechanical factor in the chest or the abdomen interfering with the diaphragmatic mobility.

Where this trial is running

Zagazig, El Sharkia

• Faculty of Medicine,Zagazig University — Zagazig, El Sharkia, Egypt (Recruiting)

Study contacts

• Principal investigator: Marwa M Medhat, M.D — zagazig university faculty of human medicine
• Study coordinator: Marwa M Medhat, M.D

Conditions of Lung Ultrasound in Diagnosis of Acute Respiratory Distress Syndrome; lung ultrasound, acute respiratory distress syndrome