Evaluating lung protection strategies in obese patients undergoing gynecological cancer surgery
The Effect of Alveolar Recruitment on Perioperative Outcomes in Obese Patients in Major Gynaecological Cancer Surgery: a Prospective Randomised Controlled Trial
This study is testing if special breathing techniques can help obese patients have fewer lung problems after major surgery for gynecological cancer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Bakirkoy Dr. Sadi Konuk Research and Training Hospital Government |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT06619626 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the impact of an alveolar recruitment strategy on postoperative pulmonary complications in obese patients undergoing major open surgeries for gynecologic cancers. The study will utilize lung protective ventilation techniques, including positive end-expiratory pressure and controlled tidal volumes, to minimize respiratory issues during recovery. Additionally, it will evaluate perioperative hemodynamics, respiratory mechanics, and the length of hospital stay for these patients. The research is conducted at a gynecological oncology clinic where such surgeries are common.
Who should consider this trial
Good fit: Ideal candidates include obese patients with a BMI between 30 and 40 kg/m2 and an ASA physical status classification of II or III.
Not a fit: Patients with a BMI over 40 kg/m2 or an ARISCAT risk score greater than 44 may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved postoperative outcomes and reduced complications for obese patients undergoing gynecological cancer surgeries.
How similar studies have performed: Similar studies have shown promising results with lung protective ventilation strategies, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with ASAII and III * BMI\>30 kg/m2 ,\<40 kg/m2 * Patients with an ARISCAT risk score of 26-44 Exclusion Criteria: * Patients with an Assessment of Respiratory Risk in Surgical Patients in Catalonia (ARISCAT) risk score \> 44 * BMI \> 40 kg/m2 patients
Where this trial is running
Istanbul
- Duygu Akyol — Istanbul, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Duygu Akyol — Başakşehir Çam & Sakura City Hospital
- Study coordinator: Duygu Akyol
- Email: dr.duyguaygun@gmail.com
- Phone: +905447616034
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.