Evaluating long-term results of knee realignment surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the long-term clinical and radiologic outcomes of high tibial osteotomy in patients with medial unicompartmental knee osteoarthritis. The procedure aims to realign the knee joint to restore proper load distribution and potentially delay the progression of arthritis. Participants will undergo follow-up assessments over a period exceeding 60 months, focusing on both clinical evaluations and X-ray imaging to monitor changes in the femoro-patellar joint. The study seeks to provide insights into the effectiveness of osteotomy as an alternative to joint replacement in younger patients with high functional demands.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Diagnosis of medial unicompartmental knee osteoarthritis (Outerbridge III-IV)
2. Follow-up \> 60 months
3. Completeness of clinical and radiographic documentation.
4. Previous valgus osteotomy procedure (MOW-HTO or LCW-HTO)
5. Age \<65 years

Exclusion Criteria:

1. Patients with previous injuries affecting the involved lower limb.
2. Patients with prior traumatic, septic, and rheumatoid arthritis.
3. Patients with previous alterations of the patellofemoral joint.
4. Patients with knee ligament injuries.
5. Patients with confirmed neuromuscular disorders or psychomotor disturbances.
6. Patients with congenital generalized hypermobility syndrome.
7. Patients with severe pathologies in other organs or systems limiting activities of daily living (ADL).
8. Patients who refuse to participate in the study.

Where it's running

• IRCCS Istituto Ortopedico Rizzoli
  Bologna, Italy Recruiting

Study contacts

• Study coordinator: Giulio Maria Marcheggiani Muccioli, MD PhD
• Email: giuliomaria.marcheggianimuccioli@ior.it
• Phone: 051 636

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.