Evaluating long-term outcomes of knee osteotomy for osteoarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the long-term and medium-term outcomes of various knee osteotomy techniques in treating knee osteoarthritis in patients with lower limb malalignment. It focuses on patients undergoing corrective knee osteotomy and associated procedures, aiming to provide insights into the effectiveness of these interventions. The study is observational and seeks to gather data on the biological treatments that can potentially delay or prevent the need for prosthetic replacement. The findings will help clarify the indications and potential of knee osteotomy as a treatment option.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients undergoing corrective knee osteotomy and any associated procedures such as meniscal repair/resection/replacement, ligament reconstruction, chondral treatment, or regenerative infiltrative treatment;
2. Patients aged between 18 and 70 years at the time of surgical intervention;
3. Patients with isolated compartmental osteoarthritis;
4. Patients with a varus or valgus knee alignment defect of at least 3° compared to mechanical neutrality.

Exclusion Criteria:

1. Patients with advanced multicompartimental osteoarthritis;
2. Patients who are no longer reachable;
3. Women of childbearing age who cannot exclude pregnancy;
4. Patients unable to give informed consent or patients unwilling to sign the informed consent form.

Where it's running

• IRCCS Istituto Ortopedico Rizzoli
  Bologna, Italy Recruiting

Study contacts

• Study coordinator: Stefano Zaffagnini
• Email: stefano.zaffagnini@ior.it
• Phone: 0516366075

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.