Evaluating long-term outcomes in patients with operable solitary liver tumors

Ten-Year Outcomes of Operable Solitary Hepatocellular Carcinoma Patients: Impact of Tumor Size Over 6.5 cm and Microvascular Invasion

Chang Gung Memorial Hospital · NCT06628661

This study looks at how the size of liver tumors and certain cancer features affect survival and recurrence in patients who have had surgery for liver cancer.

Quick facts

Study typeObservational
Enrollment3000 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorChang Gung Memorial Hospital (other)
Locations1 site (Taoyuan)
Trial IDNCT06628661 on ClinicalTrials.gov

What this trial studies

This study aims to assess the long-term outcomes of patients with operable solitary hepatocellular carcinoma (HCC) by analyzing the impact of tumor size and microvascular invasion on survival and recurrence rates. Researchers will retrospectively examine data collected from the Chang Gung Research Database, focusing on patients who underwent surgery for HCC larger than 6.5 cm. The study will classify patients based on tumor size and microvascular invasion status to evaluate outcomes across different sub-populations. This comprehensive analysis leverages a robust clinical database to provide insights into the factors influencing patient prognosis.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with operable solitary hepatocellular carcinoma.

Not a fit: Patients with non-operable HCC or those with incomplete data regarding tumor size or survival status may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify critical factors that influence survival and recurrence in HCC patients, leading to improved treatment strategies.

How similar studies have performed: Previous studies utilizing similar methodologies have shown promising results in understanding the prognostic factors in hepatocellular carcinoma.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Operable solitary hepatocellular carcinoma

Exclusion Criteria:

* Not pT1N0M0 or pT2N0M0
* Missing tumor size
* Errors in survival/recurrence dates or status

Where this trial is running

Taoyuan

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Hepatocellular Carcinoma, Solitary Mass, Hepatocellular carcinoma, Solitary tumor, Operable, Survival analysis, Tumor size, Microvacular invasion

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.