Evaluating long-term effects of gastric bypass on obesity-related diseases

Long-term Resolution of Comorbidites After Gastric Bypass

Observational Uppsala University · NCT02710786

This study looks at how gastric bypass surgery helps people with severe obesity lose weight and improve related health issues like diabetes and high blood pressure over ten years.

Quick facts

Study typeObservational
Enrollment25000 (estimated)
SexAll
SponsorUppsala University Academic / other
Locations1 site (Uppsala)
Trial IDNCT02710786 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the long-term effects of Roux-en-Y gastric bypass (RYGB) surgery on weight loss and the remission of comorbid diseases such as diabetes, hypertension, and sleep apnea in individuals with severe obesity. The study will analyze data from a large nationwide cohort over a period of ten years, focusing on the health outcomes following the surgical intervention. By utilizing the Scandinavian Obesity Surgery Registry, researchers will gather comprehensive data to evaluate the effectiveness of RYGB in improving patients' overall health.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals with severe obesity who have undergone Roux-en-Y gastric bypass surgery and are registered in the Scandinavian Obesity Surgery Registry.

Not a fit: Patients who have not undergone gastric bypass surgery or have had other types of surgical interventions will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the long-term health benefits of gastric bypass surgery for patients with severe obesity.

How similar studies have performed: Other studies have shown positive outcomes regarding weight loss and comorbidity remission following gastric bypass surgery, indicating that this approach is supported by existing evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Registered individuals in Scandinavian Obesity Surgery Registry (SOReg) having had gastric bypass

Exclusion Criteria:

* All other operations

Where this trial is running

Uppsala

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Severe Obesity
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.