Evaluating long-term effects of childhood meningitis
Long-term Sequelae of Childhood Meningitis and Meningococcal Purpura Fulminans in Ile de France: a Multidisciplinary Approach
This study is trying to see how meningococcal meningitis affects children in the long run by checking their health, learning, and development after being diagnosed.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | N/A to 17 Years |
| Sex | All |
| Sponsor | Centre Hospitalier Intercommunal Creteil Academic / other |
| Locations | 9 sites (Le Kremlin Bicêtre, Kremlin Bicêtre and 8 other locations) |
| Trial ID | NCT04685850 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the long-term sequelae of meningococcal meningitis in children who were diagnosed between 2010 and 2021. Participants will undergo a comprehensive clinical evaluation, including neurological, cognitive, auditory, speech, and visual assessments, as well as an evaluation of their academic progress. The study focuses on children from the Paris area who have been previously registered and followed for their condition. The goal is to gather data on the evolution of symptoms and challenges faced by these children beyond the first year post-diagnosis.
Who should consider this trial
Good fit: Ideal candidates are infants and children aged 0 to 17 years who have a history of meningitis or meningococcal purpura fulminans diagnosed between 2010 and 2021.
Not a fit: Patients who have not had meningitis or meningococcal purpura fulminans or those who refuse to participate will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the long-term impacts of meningococcal meningitis, leading to better management and support for affected children.
How similar studies have performed: While there is limited data on long-term outcomes of meningococcal meningitis, similar studies on childhood illnesses have shown the importance of long-term follow-up and have provided valuable insights into patient care.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Infants and children from 0 to 17 years old * Having had meningitis or meningococcal purpura fulminans between 2010 and 2021 * Delay ≥ 1 year between the date of diagnosis of meningitis or purpura meningococcal fulminans and the date of inclusion in the study (signature of the informed consent) * The holders of parental authority have read and understood the information letter and their express consent has been obtained * Patient affiliated to a social security system (Social Security or Universal Medical Coverage) Exclusion Criteria: * refusal to participate
Where this trial is running
Le Kremlin Bicêtre, Kremlin Bicêtre and 8 other locations
- CHU Bicêtre — Le Kremlin Bicêtre, Kremlin Bicêtre, France (Not_yet_recruiting)
- CHU Annecy — Annecy, France (Not_yet_recruiting)
- Centre Intercommunal de Villeneuve Saint Georges — Crosne, France (Recruiting)
- CHI créteil — Créteil, France (Recruiting)
- Groupe Hospitalier Nord Essonne — Longjumeau, France (Not_yet_recruiting)
- GHEF site de Meaux — Meaux, France (Not_yet_recruiting)
- Hôpital Necker Enfants Malades — Paris, France (Recruiting)
- Robert debré hospital — Paris, France (Recruiting)
- Ch Pontoise — Pontoise, France (Not_yet_recruiting)
Study contacts
- Study coordinator: Robert COHEN
- Email: robert.cohen@activ-france.fr
- Phone: 01 43 97 02 97
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.