Evaluating laser and cryotherapy for tooth pulp treatment
Official title: Clinical and Radiographic Evaluation Following Complete Pulpotomy Using Low Level LASER Therapy and Cryotherapy
Run by Tanta University · NCT06711081 · Data updated 2026-11-12
This study tests whether using low-level laser therapy and cryotherapy can help reduce pain and improve healing for people with severe tooth pulp issues instead of traditional root canal treatments.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 15 Years to 60 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Tanta University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Tanta) |
| Status | Recruiting |
| Started | November 2024 |
| Main results expected | December 2024 |
| Study ends | November 2025 |
| Registry record updated | December 2, 2024 |
| Trial ID | NCT06711081 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients with restorable, vital, and mature mandibular molars suffering from irreversible pulpitis.
✕Probably not a fit
Patients with active systemic diseases, periapical lesions, or significant periodontal issues may not benefit from this treatment.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effectiveness of low-level laser therapy (LLLT) and cryotherapy in performing vital pulpotomy on mature permanent molars with irreversible pulpitis. The research focuses on assessing postoperative pain levels and radiographic changes in the pulp and periodontal areas following treatment. By utilizing innovative techniques in vital pulp therapy, the study aims to enhance tooth vitality and improve long-term outcomes for patients. The approach aligns with the trend of minimally invasive endodontics, offering an alternative to traditional root canal treatments.
Why it matters
Potential benefit: If successful, this treatment could significantly reduce postoperative pain and improve the success rate of vital pulp therapy in preserving tooth vitality.
How similar studies have gone: While there is emerging interest in the use of LLLT and cryotherapy in dental treatments, this specific combination for vital pulpotomy is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Restorable vital and mature mandibular molar teeth with irreversible pulpitis. * Teeth with deep caries or large restoration. * Pre-operative radiograph showing normal periapical structure. * Teeth with normal periodontal status . Exclusion Criteria: * • Medically compromised patients with active systemic disease as uncontrolled diabetes mellitus, hypertension or cardiac diseases. * Teeth with periapical lesion. * Sinus tract or swelling. * Moderate or severe marginal periodontitis. * Patient allergic to any material or medication used in this study. * Teeth with moderate to severe mobility. * Teeth with periodontal diseases. * Teeth with anatomical variations.
Where it's running
-
Faculty of Dentistry
Tanta, Egypt Recruiting
Study contacts
- Principal investigator: abeer darrag, phd — Professor of Endodontics
- Study coordinator: mohamed motiea, bachelor
- Email: Mohamed7942staff@dent.tanta.edu.eg
- Phone: 01002249832
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.