Evaluating laser and cryotherapy for tooth pulp treatment

Clinical and Radiographic Evaluation Following Complete Pulpotomy Using Low Level LASER Therapy and Cryotherapy

NA · Tanta University · NCT06711081

This study tests whether using low-level laser therapy and cryotherapy can help reduce pain and improve healing for people with severe tooth pulp issues instead of traditional root canal treatments.

Quick facts

PhaseNA
Study typeInterventional
Enrollment30 (estimated)
Ages15 Years to 60 Years
SexAll
SponsorTanta University (other)
Drugs / interventionsradiation
Locations1 site (Tanta)
Trial IDNCT06711081 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of low-level laser therapy (LLLT) and cryotherapy in performing vital pulpotomy on mature permanent molars with irreversible pulpitis. The research focuses on assessing postoperative pain levels and radiographic changes in the pulp and periodontal areas following treatment. By utilizing innovative techniques in vital pulp therapy, the study aims to enhance tooth vitality and improve long-term outcomes for patients. The approach aligns with the trend of minimally invasive endodontics, offering an alternative to traditional root canal treatments.

Who should consider this trial

Good fit: Ideal candidates include patients with restorable, vital, and mature mandibular molars suffering from irreversible pulpitis.

Not a fit: Patients with active systemic diseases, periapical lesions, or significant periodontal issues may not benefit from this treatment.

Why it matters

Potential benefit: If successful, this treatment could significantly reduce postoperative pain and improve the success rate of vital pulp therapy in preserving tooth vitality.

How similar studies have performed: While there is emerging interest in the use of LLLT and cryotherapy in dental treatments, this specific combination for vital pulpotomy is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • Restorable vital and mature mandibular molar teeth with irreversible pulpitis.

  * Teeth with deep caries or large restoration.
  * Pre-operative radiograph showing normal periapical structure.
  * Teeth with normal periodontal status .

Exclusion Criteria:

* • Medically compromised patients with active systemic disease as uncontrolled diabetes mellitus, hypertension or cardiac diseases.

  * Teeth with periapical lesion.
  * Sinus tract or swelling.
  * Moderate or severe marginal periodontitis.
  * Patient allergic to any material or medication used in this study.
  * Teeth with moderate to severe mobility.
  * Teeth with periodontal diseases.
  * Teeth with anatomical variations.

Where this trial is running

Tanta

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: MTA Vital Tooth Pulpotomy, vital pulp therapy permanent teeth pulpotomy LLLT

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.