Evaluating joint stability in patients with collagen diseases and hypermobility
Official title: Evaluation of Functional Instability Using the "Delos Proprioceptive System" in Patients Suffering From Collagen Disease and Joint Hypermobility
Run by Istituto Ortopedico Rizzoli · NCT05871216 · Data updated 2026-11-12
This study is testing how well people with collagen diseases and joint hypermobility can keep their balance and stability during activities to see if postural corrections can help them.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Istituto Ortopedico Rizzoli Academic / other |
| Locations | 1 site (Bologna) |
| Status | Recruiting |
| Started | October 1, 2020 |
| Main results expected | March 30, 2026 |
| Study ends | March 30, 2026 |
| Registry record updated | July 20, 2025 |
| Trial ID | NCT05871216 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals with moderate to severe joint hyperlaxity as indicated by the Beighton-Horan Joint Mobility Index.
✕Probably not a fit
Patients with obesity, significant comorbidities, or those without joint hyperlaxity will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on patients suffering from collagen diseases and joint hypermobility, specifically assessing their joint stability and balance. It utilizes clinical tests and the Delos Proprioceptive System to evaluate the effectiveness of postural corrections during dynamic activities. The study aims to identify deficiencies in balance that may affect daily and sporting activities, particularly in individuals diagnosed with Joint Hypermobility Syndrome. Diagnosis is based on the Beighton score and the presence of arthralgia in multiple joints.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for patients with joint hypermobility and related conditions.
How similar studies have gone: While there is ongoing research in this area, the specific approach of using the Delos Proprioceptive System for balance evaluation in this patient population is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with moderate (Beighton-Horan Joint Mobility Index score from 3 to 4) or severe (Beighton-Horan Joint Mobility Index score from 5 to 9) joints hyperlaxity at the clinical evaluation Exclusion Criteria: * Obesity (BMI \> 25) and weight \> 90 kg * Practice of competitive sport * Orthopedic (complex surgery of the spine and lower limbs), neurological (spasticity, stroke), and oncological comorbidities * Orthostatic / walking inability * Absence of joints hyperlaxity at the clinical evaluation (Beighton-Horan Joint Mobility Index score from 0 to 2)
Where it's running
-
IRCCS-Istituto Ortopedico Rizzoli
Bologna, Italy Recruiting
Study contacts
- Study coordinator: Maria Grazia Benedetti, MD
- Email: mariagrazia.benedetti@ior.it
- Phone: +39 051 6366236
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.