Evaluating jaw contouring with hyaluronic acid filler

3-Dimensional Volumetric Analysis of a Hyaluronic Filler Injection for Jaw Contouring

Phase 4 Interventional University of Pennsylvania · NCT06694857

This study is testing if injections of a hyaluronic acid filler can change the shape of the jawline for people looking to improve their facial appearance over three months.

Quick facts

PhasePhase 4
Study typeInterventional
Enrollment15 (estimated)
Ages22 Years to 55 Years
SexAll
SponsorUniversity of Pennsylvania Academic / other
Locations1 site (Philadelphia, Pennsylvania)
Trial IDNCT06694857 on ClinicalTrials.gov

What this trial studies

This prospective evaluation focuses on analyzing volumetric changes in the lower face following injections of hyaluronic acid filler, specifically Juvéderm Volux XC, over a 90-day period. Participants will undergo 3-dimensional imaging before and after the injections to quantify changes in facial contour and asymmetry. Follow-up assessments will occur at 2 weeks, 1 month, and 3 months post-injection to monitor the effects of the treatment.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 22-55 who are interested in enhancing their jawline through filler injections.

Not a fit: Patients with prior facial fillers, cosmetic surgeries, or certain medical conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide patients with a more effective and quantifiable approach to jaw contouring using hyaluronic acid fillers.

How similar studies have performed: Previous studies on hyaluronic acid fillers have shown positive outcomes in facial contouring, indicating that this approach is supported by existing evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age 22-55
2. Patients interested in jaw contouring
3. Participants must sign the informed consent form.

Exclusion Criteria:

1Prior filler for facial contouring 2) Filler injection within the past 12 months or during duration of study 3) Prior facial cosmetic surgery (ie. facelift) 4) Prior facial trauma (ie. orbital fracture) 5) Pregnant or breastfeeding 6) Planned dental work within next 2 weeks 7) The following contraindications: patients with severe allergies manifested by a history of anaphylaxis or history or presence of multiple severe allergies, gram-positive bacterial protein allergies and lidocaine allergies

Where this trial is running

Philadelphia, Pennsylvania

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Dermal FillersJawHyaluronic AcidHA FillerHyaluronic Acid FillerFillerCosmeticFace
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.