Evaluating irrigation techniques for better root canal treatment

Effect of Different Irrigation Activating Techniques on Irrigant Penetration Depth and Microbial Reduction in Root Canals (Clinical Study)

Not applicable Interventional Tanta University · NCT06660797

This study tests different ways to clean root canals to see if they can help reduce germs and improve treatment success for people with tooth infections.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years to 40 Years
SexAll
SponsorTanta University Academic / other
Locations1 site (Tanta)
Trial IDNCT06660797 on ClinicalTrials.gov

What this trial studies

This in-vivo study aims to assess the effectiveness of various irrigation activating techniques on the penetration depth of irrigants and the reduction of microbial presence in root canals. The study focuses on primary endodontic infections, which are characterized by complex microbial profiles and challenging root canal anatomies. By comparing different activation methods, including mechanical motion and rotary instruments, the research seeks to enhance the cleaning and disinfection process during root canal treatments. The goal is to improve the overall success rates of endodontic procedures by ensuring better contact between irrigants and the canal surfaces.

Who should consider this trial

Good fit: Ideal candidates include asymptomatic patients with vital or non-vital teeth requiring root canal treatment without any systemic diseases.

Not a fit: Patients with systemic diseases, pregnant or lactating individuals, and those with specific anatomical variations or allergies may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more effective root canal treatments, reducing the risk of infection and improving patient outcomes.

How similar studies have performed: While the specific techniques being evaluated may be novel, similar studies have shown that improved irrigation methods can enhance the effectiveness of root canal treatments.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • Asymptomatic vital/non vital teeth requiring root canal treatment.

  * Teeth with sound periodontal apparatus.
  * Teeth without pus or inflammatory exudates draining through the canal.
  * Teeth without anatomic variations.
  * Teeth with sinus tract.

Exclusion Criteria:

* • Patients with any systemic diseases.

  * Pregnant or lactating patients.
  * Immunocompromised patients.
  * Apparently thin roots in which apical preparation with #40 or #50 file would be overzealous.
  * Patient allergic to anything used in this procedure especially rubber dam material and Iohexol (radiographic contrast media).

Retreatment cases. Teeth with calcified canals.

Where this trial is running

Tanta

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Irrigation ActivationEndodontic DiseaseDifferent Irrigation Activating Techniquesprimary Endodontic Infection cases
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.