Evaluating inflammatory markers in patients with certain blood disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients with Philadelphia chromosome-negative myeloproliferative neoplasms (MPN) to assess inflammatory biomarkers and their trends over the course of the disease. It aims to identify correlations between these biomarkers and disease outcomes, particularly regarding thrombo-haemorrhagic events and disease progression. By analyzing historical data, the study seeks to enhance risk stratification and improve patient management strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years at the time of diagnosis of MPN Ph negative
* Diagnosis of PV, ET, PMF or post PV and post ET MF, according to current WHO or IWG-MRT criteria (diagnosis since 2000)
* Obtaining informed consent

Exclusion Criteria:

* Life expectancy of less than 6 months
* Accelerated phase myelofibrosis or MPN with signs of leukemic evolution

Where it's running

• Azienda Ospedaliera Universitaria Consorziale Policlinico
  Bari, Italy Recruiting
• Policlinico Sant'Orsola Malpighi
  Bologna, Italy Recruiting
• ASST Spedali Civili di Brescia
  Brescia, Italy Recruiting
• Policlinico Vittorio Emanuele
  Catania, Italy Recruiting
• Ospedale Universitario Federico II
  Naples, Italy Recruiting
• Policlinico Umberto I, Università La Sapienza
  Roma, Italy Recruiting

Study contacts

• Study coordinator: Elena Maria Elli
• Email: elena.elli@libero.it
• Phone: 0392339859

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.