Evaluating HPV Testing for Cervical Cancer Screening in Women with HIV
The Value of HPV Testing for Cervical Cancer Screening in Women Living With HIV
This study is testing if using HPV testing instead of the usual cell smear can help women with HIV get better cervical cancer screenings and follow-ups.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 25 Years to 65 Years |
| Sex | Female |
| Sponsor | Centre Hospitalier de Saint-Denis Academic / other |
| Locations | 1 site (Saint-Denis) |
| Trial ID | NCT05968183 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the effectiveness of HPV testing as a screening method for cervical cancer in women living with HIV, comparing it to the traditional cell smear approach. The research will explore whether HPV testing can facilitate longer follow-up periods for patients with negative results, potentially standardizing clinical practices. By utilizing a single swab for both cytology and HPV testing, the study seeks to improve screening efficiency and patient outcomes in this population. The study is conducted at the Centre Hospitalier de Saint-Denis, where clinicians have already begun implementing this dual detection strategy.
Who should consider this trial
Good fit: Ideal candidates for this study are women aged 25-65 who are living with HIV and receiving care at the Centre Hospitalier de Saint-Denis.
Not a fit: Patients who are not HIV positive or those outside the age range of 25-65 will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved cervical cancer screening protocols for women living with HIV, enhancing early detection and reducing unnecessary procedures.
How similar studies have performed: While HPV testing has been successfully implemented in general populations, this specific evaluation in women living with HIV is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women living with HIV * Age 25-65 years * Managed in the CHSD maternity ward: consultation or hospitalization * Having signed a consent form Exclusion Criteria: * Age ≤ 24 years, or ≥ 66 years * Women who are not HIV positive * Patients under legal protection (guardianship, curatorship) * Patients deprived of liberty * Patients not affiliated to a social security system * Refusal to participate in the research
Where this trial is running
Saint-Denis
- Centre Hospitalier de Saint-Denis — Saint-Denis, France (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.