Evaluating how inhaled medications work for asthma and COPD patients
Official title: Investigation of the Relationship Between the Respiratory Profile of Patients With Obstructive Pulmonary Disease and the Effectiveness of the Inhalation Therapies
Run by Tradeflex Ltd · NCT06966271 · Data updated 2026-11-12
This study is testing how well inhaled medications work for adults with asthma and COPD by looking at their breathing patterns to see if we can improve how they use their inhalers.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Tradeflex Ltd Industry-sponsored |
| Locations | 7 sites (Budapest and 6 other locations) |
| Status | Recruiting |
| Started | January 1, 2025 |
| Main results expected | September 30, 2025 |
| Study ends | December 30, 2025 |
| Registry record updated | May 11, 2025 |
| Trial ID | NCT06966271 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old with a confirmed diagnosis of asthma or COPD who can properly use an inhalation device.
✕Probably not a fit
Patients with untreated severe chronic illnesses or those unable to complete the necessary assessments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The OPTIPULM study investigates the relationship between patients' breathing profiles and the effectiveness of inhaled therapies for asthma and chronic obstructive pulmonary disease (COPD). By analyzing pulmonary function test data, the study aims to model and estimate how well inhaled medications deposit in the lungs based on individual inhalation techniques and device characteristics. It also seeks to optimize inhaler use by providing recommendations tailored to each patient's breathing patterns. This observational study focuses on adult patients diagnosed with these conditions to improve treatment outcomes.
Why it matters
Potential benefit: If successful, this study could lead to more effective inhalation therapies tailored to individual patient needs, improving overall management of asthma and COPD.
How similar studies have gone: While the approach of modeling lung deposition based on individual breathing profiles is innovative, similar studies have shown that optimizing inhalation techniques can improve treatment outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Primary Outcome Measure: Estimated Lung Deposition of Inhaled Medication (% of Emitted Dose): The proportion of the inhaled drug dose predicted to deposit in the lungs, calculated via computer modeling using each participant's individual pulmonary function curve and inhalation parameters. Inclusion criteria: * Diagnosed obstructive pulmonary disease (asthma or COPD) confirmed by a pulmonologist. * Proper use of inhalation device after training. * Routine pulmonary function test performed during medical visit. * Ambulatory (non-hospitalized) patient. * Age over 18 years. * Mentally competent and able to consent. Exclusion criteria: * Failure to meet any of the inclusion criteria. * Inability to complete the relevant parts of the questionnaire. * Refusal to consent to participation. * Presence of untreated severe chronic illness. * Invalid or improperly conducted pulmonary function test.
Where it's running
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Református Pulmonológiai Centrum
Törökbálint, Hungary Recruiting -
Országos Korányi Pulmonológiai Intézet
Budapest, Hungary Not yet recruiting -
Csornai Margit Kórház Pulmonológiai és Allergológia Szakambulancia
Csorna, Hungary Not yet recruiting -
Debreceni Egyetem Tüdőgyógyászati Klinika
Debrecen, Hungary Not yet recruiting -
Dunakeszi-SZTK Nonprofit Kft. Tüdőgyógyászat
Dunakeszi, Hungary Not yet recruiting -
Győr-Moson-Sopron Vármegyei Petz Aladár Egyetemi Oktató Kórház
Győr, Hungary Not yet recruiting
Show 1 more location
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• Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ Tüdőgyógyászati Klinika
Szeged, Hungary Not yet recruiting
Study contacts
- Principal investigator: János Varga, Prof. — Semmelweis University
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.