Evaluating how endoscopic lung volume reduction affects diaphragm function
Effects of Endoscopic Lung Volume Reduction on Diaphragm Function and Conformation
NA · Erasme University Hospital · NCT05799352
This study is testing how a lung procedure called endoscopic lung volume reduction affects the diaphragm's function in people with COPD.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Erasme University Hospital (other) |
| Locations | 1 site (Brussels) |
| Trial ID | NCT05799352 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of endoscopic lung volume reduction (ELVR) on diaphragm function and structure in patients with chronic obstructive pulmonary disease (COPD). By focusing on the changes in diaphragmatic conformation and function following the procedure, the research aims to clarify the mechanisms behind the respiratory improvements observed with ELVR. The study will involve patients undergoing valve insertion as part of the ELVR intervention, assessing their diaphragmatic performance pre- and post-procedure.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with COPD who are eligible for endoscopic lung volume reduction involving valve insertion.
Not a fit: Patients with a total lung volume reduction of less than 50% may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for COPD patients, enhancing their respiratory function and quality of life.
How similar studies have performed: Previous studies on lung volume reduction techniques have shown positive outcomes, suggesting that this approach may also yield beneficial results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * valves insertion Exclusion Criteria: * TLVR \< 50 %
Where this trial is running
Brussels
- Erasme Hospital — Brussels, Belgium (RECRUITING)
Study contacts
- Principal investigator: Olivier Taton — Hôpital Erasme, Université Libre de Brussels, Brussels, Belgium
- Study coordinator: Olivier Taton
- Email: olivier.taton@hubruxelles.be
- Phone: 025553943
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: COPD