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Clinical trial No longer in our active list Observational Ages 18 and up

Evaluating heart volume using real-time MRI

Official title: Comparison of Standard Breath-hold Cardiac MRI With a Faster, Free-breathing Scan

Run by University of Leicester · NCT05221853 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing if a new real-time MRI technique can more accurately measure heart size and function in patients with heart problems compared to the standard method.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment570 (estimated)
SponsorUniversity of Leicester
Academic / other
Locations1 site (Leicester, Leics)
Trial IDNCT05221853 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older who are referred for routine CMR imaging and can provide informed consent.

Probably not a fit

Patients with severe claustrophobia or absolute contraindications to CMR will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to compare the accuracy of a real-time Cine sequence with standard multi-breath-hold imaging in assessing cardiac volumetry in patients with known or suspected cardiac disease. Conducted at Glenfield General Hospital in Leicester, it will involve up to 570 patients referred for routine cardiovascular magnetic resonance (CMR) assessments. The primary focus is on measuring various cardiac volumes and functions, while secondary outcomes include scan time and image quality. Participants will undergo both imaging techniques to determine the effectiveness of the real-time approach.

Why it matters

Potential benefit: If successful, this study could enhance the accuracy and efficiency of cardiac volumetry assessments, leading to better patient management.

How similar studies have gone: While this approach is innovative, similar studies have shown promise in improving imaging techniques, suggesting potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

1. Patients aged ≥ 18 years
2. Referred for routine CMR imaging
3. Willing and able to give informed consent
4. Willing and able to comply with the requirements of the study
5. Able to understand written English

Exclusion Criteria:

1. Severe claustrophobia
2. Absolute contraindications to CMR (those with CMR conditional or safe devices will be eligible for inclusion)
3. Unable to provide informed consent
4. Participants unable to understand written English

Where it's running

  • Glenfield Hospital
    Leicester, Leics, United Kingdom     Recruiting

Study contacts

  • Principal investigator: Jayanth Arnold — University of Leicester
  • Study coordinator: Jayanth Arnold, BMBCh
  • Email: jra14@le.ac.uk
  • Phone: 01162583038

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.