Evaluating heart volume using real-time MRI
Comparison of Standard Breath-hold Cardiac MRI With a Faster, Free-breathing Scan
University of Leicester · NCT05221853
This study is testing if a new real-time MRI technique can more accurately measure heart size and function in patients with heart problems compared to the standard method.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 570 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Leicester (other) |
| Locations | 1 site (Leicester, Leics) |
| Trial ID | NCT05221853 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare the accuracy of a real-time Cine sequence with standard multi-breath-hold imaging in assessing cardiac volumetry in patients with known or suspected cardiac disease. Conducted at Glenfield General Hospital in Leicester, it will involve up to 570 patients referred for routine cardiovascular magnetic resonance (CMR) assessments. The primary focus is on measuring various cardiac volumes and functions, while secondary outcomes include scan time and image quality. Participants will undergo both imaging techniques to determine the effectiveness of the real-time approach.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are referred for routine CMR imaging and can provide informed consent.
Not a fit: Patients with severe claustrophobia or absolute contraindications to CMR will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy and efficiency of cardiac volumetry assessments, leading to better patient management.
How similar studies have performed: While this approach is innovative, similar studies have shown promise in improving imaging techniques, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients aged ≥ 18 years 2. Referred for routine CMR imaging 3. Willing and able to give informed consent 4. Willing and able to comply with the requirements of the study 5. Able to understand written English Exclusion Criteria: 1. Severe claustrophobia 2. Absolute contraindications to CMR (those with CMR conditional or safe devices will be eligible for inclusion) 3. Unable to provide informed consent 4. Participants unable to understand written English
Where this trial is running
Leicester, Leics
- Glenfield Hospital — Leicester, Leics, United Kingdom (RECRUITING)
Study contacts
- Principal investigator: Jayanth Arnold — University of Leicester
- Study coordinator: Jayanth Arnold, BMBCh
- Email: jra14@le.ac.uk
- Phone: 01162583038
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Left Ventricle Abnormality