Evaluating heart function in children with nephrotic syndrome
Cardiac Performance Evaluation in Children With Steroid Dependent vs Steroid Resistant Nephrotic Syndrome
This study is testing how nephrotic syndrome affects heart function in children who rely on steroids compared to those who don’t, using safe imaging techniques to spot any heart problems early.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 2 Years to 14 Years |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06622915 on ClinicalTrials.gov |
What this trial studies
This study evaluates cardiac performance in children diagnosed with nephrotic syndrome, comparing those who are steroid-dependent to those who are steroid-resistant. It utilizes non-invasive imaging techniques, specifically Tissue Doppler imaging and Conventional Echocardiography, to assess myocardial dysfunction. The goal is to understand the impact of nephrotic syndrome on heart health in pediatric patients. By identifying cardiac issues early, the study aims to improve management strategies for affected children.
Who should consider this trial
Good fit: Ideal candidates are children aged 2 to 14 years diagnosed with primary nephrotic syndrome.
Not a fit: Patients with primary cardiac diseases or those who refuse to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better cardiac care and management for children suffering from nephrotic syndrome.
How similar studies have performed: While there is existing research on cardiac issues in nephrotic syndrome, this specific approach using Tissue Doppler imaging is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children with primary nephrotic syndrome. * Age: 2 - 14 years. * Both males and females Exclusion Criteria: * Patients of primary cardiac diseases (e.g., congenital or rheumatic heart disease, cardio- myopathy). Patients who refuse to give written informed consent to study
Where this trial is running
Sohag
- Sohag University hospitals — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: alaa y Mohamed, Resident
- Email: alaa.yehya@med.sohag.edu.eg
- Phone: 01094667344
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.