Evaluating head-up CPR for patients with cardiac arrest
The Feasibility and Safety of Head-up Cardiopulmonary Resuscitation in Patients With Non-traumatic Cardiac Arrest: Single Center Research
This study is testing a new way of doing CPR while the patient is sitting up to see if it is safe and helps people who have had a cardiac arrest.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT05609357 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the feasibility and safety of head-up cardiopulmonary resuscitation (CPR) in patients experiencing non-traumatic cardiac arrest. Participants will receive head-up CPR during resuscitation, utilizing an impedance threshold device and active compression-decompression techniques. The study aims to assess any adverse events that may occur during this innovative resuscitation approach, building on previous animal model findings that suggest improved cerebral and coronary perfusion pressure.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 20 and older who have experienced non-traumatic cardiac arrest.
Not a fit: Patients with traumatic cardiac arrest, those under 20 years of age, or individuals with irreversible death or cervical spine disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance resuscitation outcomes and increase the rates of return of spontaneous circulation in cardiac arrest patients.
How similar studies have performed: While this approach has shown promise in animal models, its application in human subjects is novel and has not been extensively tested in previous studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Non-traumatic cardiac arrest * Age ≥ 20 Exclusion Criteria: * Trauma * Age \< 20 * Pregnancy * Irreversible death (e.g. liver mortis, rigor mortis, decapitation, transection and decomposition) * Disorder of cervical spine
Where this trial is running
Taipei
- National Taiwan University Hospital — Taipei, Taiwan (Recruiting)
Study contacts
- Principal investigator: Wei-Ting Chen — National Taiwan University Hospital
- Study coordinator: Chih-Hsien Lin
- Email: 47ienn@gmail.com
- Phone: +886972653698
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.