Evaluating Glofitamab with Salvage Therapy for B-cell Non-Hodgkin Lymphoma in Adults

A Prospective, Observational Study to Explore the Efficacy and Safety of Salvage Therapy With Glofitamab in a Real-world Setting in Chinese Adult Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma.

The First Affiliated Hospital of Soochow University · NCT06497452

This study is testing if adding glofitamab to standard treatments can help adults in China with relapsed or hard-to-treat B-cell non-Hodgkin lymphoma feel better.

Quick facts

Study typeObservational
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorThe First Affiliated Hospital of Soochow University (other)
Drugs / interventionsglofitamab
Locations1 site (Suzhou, Jiangsu)
Trial IDNCT06497452 on ClinicalTrials.gov

What this trial studies

This study aims to assess the efficacy and safety of glofitamab in combination with salvage therapy in a real-world setting among Chinese adults diagnosed with relapsed or refractory B-cell non-Hodgkin lymphoma. Participants will receive glofitamab as part of their treatment regimen, and the study will monitor outcomes related to their response to therapy. The observational nature of the study allows for the collection of data from routine clinical practice rather than a controlled environment.

Who should consider this trial

Good fit: Ideal candidates for this study are Chinese adults who have been diagnosed with relapsed or refractory B-cell non-Hodgkin lymphoma and are set to receive glofitamab.

Not a fit: Patients currently participating in other interventional clinical trials or deemed unsuitable by the investigator will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a new effective treatment option for patients with difficult-to-treat B-cell non-Hodgkin lymphoma.

How similar studies have performed: While this specific approach is being evaluated in a real-world setting, similar studies have shown promise in assessing the efficacy of glofitamab in treating B-cell non-Hodgkin lymphoma.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Be diagnosed as B-NHL
* Relapse or refractory to previous treatment
* Participants who will be treated with glofitamab

Exclusion Criteria:

* Participant who currently participates in or with plan to participate in any interventional clinical trial
* Any other reason that, in the investigator's opinion, makes the participant unsuitable to participate in this study.

Where this trial is running

Suzhou, Jiangsu

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: B-cell Non-Hodgkin Lymphoma

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.