Evaluating fluid responsiveness after heart surgery

Evaluation of Fluid Responsiveness With Recruitment Maneuver After Sternotomy in Coronary Artery Bypass Surgery

Observational Ankara City Hospital Bilkent · NCT06249568

This study is testing if a specific breathing technique can help doctors understand how much fluid heart surgery patients need after their operation.

Quick facts

Study typeObservational
Enrollment45 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorAnkara City Hospital Bilkent Academic / other
Locations1 site (Ankara)
Trial IDNCT06249568 on ClinicalTrials.gov

What this trial studies

This study aims to assess fluid responsiveness in patients undergoing elective coronary artery bypass surgery by measuring hemodynamic parameters before and after a lung recruitment maneuver. Researchers will monitor stroke volume index, cardiac index, and mean arterial pressure while patients are positioned appropriately. Following a lung opening maneuver, they will evaluate changes in these parameters to determine the effectiveness of the maneuver in predicting fluid needs. The study focuses on patients ventilated with a specific lung volume to enhance the reliability of dynamic indices.

Who should consider this trial

Good fit: Ideal candidates are ASA2-3 patients aged 18-80 scheduled for elective coronary bypass surgery.

Not a fit: Patients with severe comorbidities, such as significant heart or lung disease, or those outside the age range may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve fluid management in coronary artery bypass surgery patients, potentially leading to better surgical outcomes.

How similar studies have performed: While similar approaches have been explored, this specific evaluation of fluid responsiveness using a lung recruitment maneuver in this patient population is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
* Inclusion Criteria:
* 1-ASA2-3 patients between the ages of 18-80 who will undergo elective coronary bypass surgery under general anesthesia
* Exclusion Criteria:
* 1\. Be younger than 18 years old, be over 80 years old
* 2\. Patients with an ASA score greater than 3
* 3\. EF\<40%
* 4\. Those with contraindications to anesthetic drugs
* 5\. Patients with BMI\>30
* 6\. Patients who did not want to participate in the study
* 7\. Right ventricular dysfunction
* 8\. COPD(Chronic obstructive pulmonary disease)
* 9\. Bullous lung disease
* 10\. Moderate to severe PHT
* 11\. Severe kidney or liver disease
* 12\. Patients with hemodynamic instability in the perioperative period
* 13\. Pregnancy

Where this trial is running

Ankara

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Fluid TherapyCoronary Artery Bypass Surgery PatientsLung Recruitment Maneuverfluid therapy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.