Evaluating exercise testing for diagnosing coronary artery blockages
Evaluation of the Predictive Power of Double-product Increase Measured During an Exercise Test for the Prediction of Coronary Stenosis As Diagnosed by Cardiac CT Scan or Coronary Angiography.
This study is testing if exercise testing on a bike can help find blockages in the heart's arteries for people who might have coronary artery disease, so they might not need more invasive tests.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Sud Francilien Academic / other |
| Locations | 1 site (Corbeil-Essonnes, France) |
| Trial ID | NCT05140434 on ClinicalTrials.gov |
What this trial studies
This observational study aims to determine the effectiveness of exercise testing in detecting obstructions in coronary arteries, potentially reducing the need for invasive imaging procedures. Patients suspected of having coronary artery disease will undergo an exercise test on a bike while their EKG, blood pressure, and other parameters are monitored. The study will analyze the relationship between double product (a measure of myocardial oxygen consumption) during exercise and the presence of significant coronary artery stenosis, using data from both exercise tests and imaging studies conducted within a three-month period.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who have undergone both exercise testing and cardiac imaging within the specified timeframe.
Not a fit: Patients who are unable to understand the study information or cannot participate in exercise testing will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to less invasive diagnostic methods for patients with coronary artery disease.
How similar studies have performed: Other studies have shown promise in using exercise testing for diagnosing coronary artery disease, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Starting betweew 1/1/2019 and 3/1/2022 * 18 year-old patients or older * Patients with both exercise testing and either Cardiac CT or coronary angiography within 3 months * Patients informed and not opposing to their participation to the study Exclusion Criteria: * Patients unable to fully understand the information related to the study
Where this trial is running
Corbeil-Essonnes, France
- CHARANSONNEY Olivier — Corbeil-Essonnes, France, France (Recruiting)
Study contacts
- Principal investigator: Olivier CHARANSONNEY, MD — Centre Hospitalier Sud Francilien
- Study coordinator: Olivier CHARANSONNEY, MD
- Email: olivier.charansonney@chsf.fr
- Phone: 0161697766
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.