Evaluating epileptic syndromes in infants and young children
Clinico-etiological Profile of Epileptic Syndromes in Infants and Early Childhood
Al-Azhar University · NCT06223334
This study is trying to learn more about different types of epilepsy in babies and young children to see how common they are and what causes them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 140 (estimated) |
| Ages | 1 Month to 36 Months |
| Sex | All |
| Sponsor | Al-Azhar University (other) |
| Locations | 2 sites (Assiut and 1 other locations) |
| Trial ID | NCT06223334 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the various clinical and etiological patterns of epileptic syndromes in infants and early childhood. It focuses on understanding the incidence and characteristics of epilepsy that begins before the age of two, which is often symptomatic and associated with poor long-term outcomes. The study will analyze cases based on recent genetic discoveries and traditional electroclinical features to provide a comprehensive overview of these syndromes. By examining a population-based cohort, the study seeks to fill gaps in knowledge regarding the prevalence and nature of epilepsy in resource-limited settings.
Who should consider this trial
Good fit: Ideal candidates for this study are infants and children aged 1 to 36 months diagnosed with an epileptic syndrome according to the International League Against Epilepsy criteria.
Not a fit: Patients with epilepsy diagnosed before 1 month or after 36 months, or those with conditions that mimic epilepsy, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of epileptic syndromes in young children, potentially enhancing treatment outcomes.
How similar studies have performed: While this study builds on previous work regarding epilepsy in infants, it aims to provide a broader perspective that has not been extensively explored in resource-limited settings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: For each group * Infants and children diagnosed as epilepsy syndrome (as per International League Against Epilepsy, 2014). * Infants and children ages ranged between 1 \& 36 months. Exclusion Criteria: for each group * Patients with epilepsy less than 1 month and more than 36 months. * Patients with conditions mimic epilepsy. * Patients with seizures related to electrolyte disturbances, inborn error of metabolism, mitochondrial diseases, white matter diseases, neurodegenerative diseases, peroxisomal disorders and non-syndromic epileptic children.
Where this trial is running
Assiut and 1 other locations
- Assiut child university hospital — Assiut, Egypt (RECRUITING)
- AlAzhar university hospital Assiut branch — Assiut, Egypt (RECRUITING)
Study contacts
- Principal investigator: Amir Abdelaal Hasanain Abdelrahman — Al-Azhar University
- Study coordinator: Amir Abdelaal Hasanain Abdelrahman
- Email: dr_amir.makhlof@yahoo.com
- Phone: 01022086737
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Epileptic Syndromes, infants, early childhood