Evaluating effects of different electrical stimulation patterns in epilepsy patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the modulation effects of various electrical stimulation patterns in patients with drug-resistant epilepsy who have SEEG electrodes implanted. It compares single-pulse, paired-pulse, stepwise frequency, and burst stimulation to assess their impact on focal and network modulation during resting and post-seizure states. The research aims to enhance understanding of how different stimulation paradigms can influence seizure activity and brain function.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Drug-resistant focal epilepsy
* Justified SEEG exploration in the context of presurgical assessment of epilepsy
* Subjects will be a part of the epilepsy-monitoring unit for long-term SEEG recordings and analysis
* Written non-opposition to study participation

Exclusion Criteria:

* Pregnant women (Contraindication to SEEG exploration)
* Psychiatric disorders
* History of psychotic disorders
* History of cranial trauma serious (according to the classification), previous or evolutionary other neurological pathology
* Subjects that experience surgical complications during the implant procedure will be excluded from the study

Where it's running

• Xuanwu Hospital,Capital Medical University
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Liankun Ren, MD — Xuanwu Hospital, Beijing
• Study coordinator: Liankun Ren, MD
• Email: renlk2022@outlook.com
• Phone: +86 13681576621

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.