Evaluating EEG Features for Predicting Cognitive Disorders After Heart Surgery
Official title: To Explore the Predictive Value of Electroencephalography Features in Perioperative Neurocognitive Disorders in Patients Undergoing Cardiovascular Surgery Under General Anaesthesia: a Single-centre Prospective Observational Study
Run by Beijing Chao Yang Hospital · NCT06692309 · Data updated 2026-11-12
This study is testing if brain activity measured by EEG can help predict if heart surgery patients will have memory or thinking problems after their operation.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 60 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Beijing Chao Yang Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | March 1, 2023 |
| Main results expected | August 31, 2025 |
| Study ends | February 28, 2026 |
| Registry record updated | May 30, 2025 |
| Trial ID | NCT06692309 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients over 60 years old who are scheduled for coronary artery bypass surgery or valve replacement surgery under general anesthesia.
✕Probably not a fit
Patients with severe neurological or psychiatric diseases, or those with significant impairments that prevent them from completing cognitive tests, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to investigate how electroencephalography (EEG) features can predict the occurrence of perioperative neurocognitive disorders in patients undergoing cardiovascular surgery with general anesthesia. Data will be collected using a standard 32-channel EEG cap, and cognitive assessments will be performed before and after the surgery using the Montreal Cognitive Assessment (MoCA). The study will analyze preoperative and postoperative EEG brain network-related indexes to identify potential predictive markers for cognitive decline following surgery.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for predicting and managing cognitive disorders in patients undergoing heart surgery.
How similar studies have gone: While the predictive value of EEG in cognitive disorders is an emerging field, similar studies have shown promising results in identifying cognitive decline post-surgery.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Written informed consent 2. undergoing coronary artery bypass surgery or valve replacement surgery under general anaesthesia 3. ASA grade: II-IV 4. older than 60 years 5. Able to complete cognitive function tests Exclusion criteria: 1. history of severe neurological diseases and psychiatric diseases 2. history of drug abuse 3. severe hearing or vision impairment 4. preoperative delirium 5. serious adverse reactions such as cardiac arrest and cardiopulmonary resuscitation during surgery 6. patients undergoing secondary surgery in a short period 7. participation in concurrent clinical trials
Where it's running
-
Beijing Chao Yang Hospital
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Principal investigator: Anshi Wu, doctor — Beijing Chao Yang Hospital
- Study coordinator: Changwei Wei, doctor
- Email: changwei.wei@ccmu.edu.cn
- Phone: 13810678936
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Biomarkers to predict CSA-AKI risk before heart surgery
This study tests new biomarkers to see if they can predict CSA-AKI risk in adults undergoing cardiovascular surgery.
-
Can a phone version of the Mini-Cog identify cognitive impairment before surgery?
This study tests whether a telephone-based Mini-Cog can reliably detect cognitive impairment in adults 65 and older before they have surgery.
-
Appropriateness of Hemostatic Agent Use in Cardiovascular Surgery
This study tests how well surgeons’ choices about topical hemostatic agents match current guidelines in cardiac and vascular surgery at one Milan hospital.
-
PIFPB-based blocks to aid pain relief after cardiac surgery
This observational study tests whether combining a pectoral-intercostal fascial plane block with either a recto-intercostal fascial plane block or a rectus sheath block can improve postoperative pain control for adults undergoing elective cardiac surgery.
-
Nutrition and gut metabolites in heart surgery patients
This will try a postoperative probiotic supplement in people having cardiovascular surgery to see if changing gut-derived metabolites improves blood metabolic markers and recovery.
-
6-week gut microbiome prep before heart surgery to see if it improves outcomes and saves NHS costs
A 6-week preoperative test using WellBiome or placebo in people needing heart surgery to see if gut bacteria changes can improve recovery and reduce costs.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.