Evaluating EEG Features for Predicting Cognitive Disorders After Heart Surgery
To Explore the Predictive Value of Electroencephalography Features in Perioperative Neurocognitive Disorders in Patients Undergoing Cardiovascular Surgery Under General Anaesthesia: a Single-centre Prospective Observational Study
This study is testing if brain activity measured by EEG can help predict if heart surgery patients will have memory or thinking problems after their operation.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 60 Years and up |
| Sex | All |
| Sponsor | Beijing Chao Yang Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Trial ID | NCT06692309 on ClinicalTrials.gov |
What this trial studies
This study aims to investigate how electroencephalography (EEG) features can predict the occurrence of perioperative neurocognitive disorders in patients undergoing cardiovascular surgery with general anesthesia. Data will be collected using a standard 32-channel EEG cap, and cognitive assessments will be performed before and after the surgery using the Montreal Cognitive Assessment (MoCA). The study will analyze preoperative and postoperative EEG brain network-related indexes to identify potential predictive markers for cognitive decline following surgery.
Who should consider this trial
Good fit: Ideal candidates for this study are patients over 60 years old who are scheduled for coronary artery bypass surgery or valve replacement surgery under general anesthesia.
Not a fit: Patients with severe neurological or psychiatric diseases, or those with significant impairments that prevent them from completing cognitive tests, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for predicting and managing cognitive disorders in patients undergoing heart surgery.
How similar studies have performed: While the predictive value of EEG in cognitive disorders is an emerging field, similar studies have shown promising results in identifying cognitive decline post-surgery.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Written informed consent 2. undergoing coronary artery bypass surgery or valve replacement surgery under general anaesthesia 3. ASA grade: II-IV 4. older than 60 years 5. Able to complete cognitive function tests Exclusion criteria: 1. history of severe neurological diseases and psychiatric diseases 2. history of drug abuse 3. severe hearing or vision impairment 4. preoperative delirium 5. serious adverse reactions such as cardiac arrest and cardiopulmonary resuscitation during surgery 6. patients undergoing secondary surgery in a short period 7. participation in concurrent clinical trials
Where this trial is running
Beijing, Beijing Municipality
- Beijing Chao Yang Hospital — Beijing, Beijing Municipality, China (Recruiting)
Study contacts
- Principal investigator: Anshi Wu, doctor — Beijing Chao Yang Hospital
- Study coordinator: Changwei Wei, doctor
- Email: changwei.wei@ccmu.edu.cn
- Phone: 13810678936
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.